New Products

Feb 03, 2017

Meridian Bioscience TruQuick

Meridian Bioscience has launched TruQuick, a comprehensive point-of-care product menu of rapid tests for the diagnosis of tropical, infectious, sexually transmitted, respiratory, gastrointestinal, cancer, and cardiac diseases. TruQuick is a qualitative lateral flow chromatographic immunoassay menu of over 60 products. Its rapid tests can aid in the diagnosis of infectious pathogens and other important acute diseases in 10 to 20 minutes, the company said. 

Feb 02, 2017

Biodesix's GeneStrat Includes ROS1 and RET Mutations

Biodesix has broadened its GeneStrat liquid biopsy test to include ROS1 and RET mutations in addition to EGFR sensitizing, EGFR resistance, KRAS, BRAF, and EML4-ALK alterations.

GeneStrat is a part of the Biodesix's larger "Lung Reflex" multi-omic liquid biopsy testing strategy, which also includes the VeriStrat proteomic testing. With results available within 72 hours, the company says that GeneStrat and VeriStrat together deliver comprehensive information for physicians to support critical treatment decisions at initial diagnosis, expediting appropriate treatment.

Feb 02, 2017

Sygnis TrueHelix

Sygnis has launched TrueHelix, a web-accessible bioinformatics platform for next-generation sequencing analysis services.

The first tool released on it will be TruePure, a sample purity validation service that checks for contamination from environmental or other sources.

Sygnis plans to add more tools over the rest of the year.

Jan 31, 2017

Benchling Molecular Biology 2.0

Research software firm Benchling has announced the release of its Molecular Biology 2.0 system. 

The extension to its platform incorporates batch sequence design, CRISPR design, protein design, alignment tools, and cloning software into its digital lab notebook, enabling high-throughput antibody engineering and CRISPR design. 

Jan 25, 2017

Mawi DNA Technologies ISWAB-Microbiome

Mawi DNA Technologies has launched the iSWAB-Microbiome, a biosampling tool designed to collect and stabilize microbial content and diversity within gut, rectal, vaginal, skin, oral, or soil samples for processing. The tool was developed to produce an accurate representation of the microbiota composition without loss of any taxa from the point of collection to processing, to provide researchers with the ability to analyze microbiome with minimal host gDNA contamination, and to enable analysis of the microbiome DNA and RNA from the same sample, the company said.

Jan 25, 2017

Cancer Genetics Focus::HERSite

Cancer Genetics has launched Focus::HERSite, a genomic panel for hereditary breast and ovarian cancer syndrome. The panel analyzes the 16 most common genes associated with breast and ovarian cancers. It also provides comprehensive coverage of BRCA1 and BRCA2, with the ability to detect large genomic rearrangements, duplications, and deletions in those genes, the company said.

Jan 25, 2017

Intermountain Precision Genomics ICG100 Panel Expansion

Intermountain Precision Genomics announced today the expansion of the ICG100 panel, a test which identifies mutations, and then targets mutations with a personalized therapy. The panel expansion includes 162 genes often associated in cancer pathways. The panel is approved for late stage cancer patients who have failed to receive results from a traditional treatment method.

Jan 25, 2017

Takara Bio In-Fusion Cloning Primer Design Tool

Takara Bio subsidiary Takara Bio USA has launched the In-Fusion Cloning Primer Design Tool. The free online tool is powered by TeselaGen Biotechnology software, and provides researchers with a method to seamlessly join together linear fragments of DNA in a single, 15-minute reaction. It can support a wide range of cloning applications, including multi-fragment cloning, mutagenesis, and general cloning.

Jan 24, 2017

GenePeeks Virtual Progeny Analytics

GenePeeks launched the Virtual Progeny Analytics screening platform for reporting individual carrier status for a limited number of diseases. The technology digitally combines genetic information from two prospective parents to generate and analyze potential genetic combinations, enabling high-resolution visibility into the risk of conceiving a child with one of more than 1,000 inheritable genetic diseases, the company said. 

Jan 20, 2017

SoftGenetics ChimerMaker Software Update

SoftGenetics has launched the latest version of its ChimerMaker software, an automated chimerism analysis software. The latest version incorporate new workflow functionalities to meet the needs of leading edge HLA, molecular pathology, histocompatibility, transplant, and immunology laboratories. In addition, the software is now compatible with the company's Six Dye Chemistries, enabling labs to analyze results from more loci from human ID kits, the company said.

Jan 20, 2017

Becton Dickinson Precise WTA Kits for Single-Cell Research

Becton Dickinson has launched the BD Precise WTA kits, which provide an easier method to identify and quantify genetic information in single cells. The kits include specialized reagents that can extract RNA molecules from individual cells and then "tag" each molecule with a unique molecular signature. Researchers stain a sample with dyes and insert the treated sample into a flow cytometer where the cells are lysed, barcoded, and further prepared for sequencing. Once sequenced, the cell data is processed and analyzed by a proprietary analysis pipeline specific for RNA quantification.

Jan 20, 2017

Phase Genomics Proximo

Phase Genomics has launched Proximo, a service providing complete end-to-end genome assemblies to researchers around the globe. To create the assemblies, the company uses a modified version of the chromosome capture method, Hi-C, to measure the distances between DNA sequence. Then the company uses its proprietary software to organize DNA sequence fragment into whole chromosomes based on those measurements.

Jan 20, 2017

Dovetail Genomics Hi-C Sequencing and Assembly Service

Dovetail Genomics has launched its Dovetail Hi-C sequencing and assembly service, which yields chromosome-scale genome assemblies. The new Dovetail Hi-C service produces libraries that enables researchers to look at biological signals and chromosome rearrangements through the lens of in vivo chromatin interactions.

Jan 18, 2017

Cambridge Isotope Laboratories Mouse Express NeuCode

Cambridge Isotope Laboratories has launched Mouse Express NeuCode, a mouse feed with various combinations of labeled Lys isotopologues for MS proteomics studies. The product will increase the multiplexing potential for traditional SILAC quantitative experiments involving neuron encoding. It uses isotopologues of lysine for multiplexed relative quantification of proteins by high-resolution MS. NeuCode also drastically cuts down on labeling time compared to SILAM and allows detection of a greater number of peptides than SILAC, the company said. The product is available in one-week or three-week quantities, and each kit contains enough feed for three mice.

Jan 11, 2017

Celmatix Fertilome

Celmatix has launched Fertilome, a genetic screen that reveals how a woman's DNA may influence her reproductive health. The test analyzes a patient's blood samples for genetic factors associated with the most common reproductive conditions that can lead to fertility difficulties in women, including endometriosis, polycystic ovarian syndrome, and primary ovarian insufficiency. Fertilome is available through physicians.

Jan 11, 2017

Dolomite Bio Injection Valve and Sample Loop

Dolomite Bio has launched a Injection Valve and Sample Loop for single cell RNA sequencing workflows. The product is a complete four-way valve module which allow barcoded mRNA capture beads in lysis buffer to efficiently flow through the RNA-Seq chip. Its design and simple microfluidic connections enable seamless switching between the injection of the bead suspension and pumping of a driving fluid. This produces minimal dead volume and bead wastage compared to traditional syringe pump methods, the company said.

Jan 11, 2017

Bioline EPIK MiRNA Select Assays

Meridian Bioscience subsidiary Bioline has launched a full range of EPIK miRNA Select assays. The recent release includes all of the organisms listed on the miRBase release 21, which increases the number of EPIK miRNA assays to over 27,000. Each assay was designed in collaboration with MiRXES in silico using thermodynamics-based algorithms. They also include miRNA specific reverse transcriptase primers and hemi-nested real-time PCR primers along with Bioline reverse transcriptase, SensiSmart with SYBR Green, and optimized buffers.

Jan 09, 2017

Cynvenio ClearID Breast Cancer Test

Cynvenio Biosystems released its updated ClearID Breast Cancer blood test, which leverages a custom-developed NGS panel of 27 genes known to be altered in breast cancer. The updated test identifies circulating tumor cell burden and detects emerging genetic alterations that are associated with therapy resistance. The assay has been optimized to monitor patients with advanced breast cancer during the start of therapy and at regular intervals following treatment. 

Jan 09, 2017

Pacific Biosciences Sequel Chemistry and Software Update

Pacific Biosciences has launched a new chemistry, V2, and new software, V4, for its Sequel sequencing system that will be available on Jan. 23. The release also includes a new version of the consumable SMRT cells. The updates improve the system's ability to support applications such as structural variant detection and targeted sequencing for tasks such as metagenomics, minor variant detection, and isoform sequencing. The mean read length is now 10 to 18 kilobases, with half the data in reads larger than 20 kilobases. Throughput is now 5 to 8 gigabases, depending on sample type and sample prep method used. The system is now also capable of loading 80-kilobase sequencing libraries. The new software includes updates to the base-calling algorithm that increase accuracy and new features to the system software to support clinical research applications.

Jan 05, 2017

Core Informatics Sanger Sequencing and Microarray Genotyping Apps

Core Informatics has released two applications for its Platform for Science that are designed to help researchers execute microarray genotyping and Sanger sequencing workflows. The company's Sanger sequencing application provides data management tools for small-scale projects in both regulated and non-regulated laboratory environments. It includes capabilities for analyzing long reads as well as for validating next-generation sequencing results. The microarray genotyping application lets users track samples as well as capture and manage data as part of large-scale genotyping projects.

Jan 05, 2017

Baylor Genetics PreSeek for Prenatal Multi-Gene Sequencing Screen

Baylor Genetics has launched PreSeek, a clinical non-invasive prenatal multi-gene sequencing screen. The test requires blood and/or saliva samples from each parent, then sequences cell-free fetal DNA for de novo disease-causing variants associated with select single-gene conditions affecting the skeletal, cardiac, and neurological systems. It is complementary to traditional prenatal screening tests, the company said.

Jan 03, 2017

Fluidigm C1 Medium-Cell High-Throughput IFC

Fluidigm has released its new high-throughput integrated fluidic circuit (HT IFC) for isolating medium-sized single cells using the firm's C1 system for mRNA sequencing. The device captures up to 800 single cells, between 10 and 17 micrometers, at higher capture efficiency and comes with live, on-IFC imaging for viability and phenotypic analysis. The firm added that the new chip enables scaling of cell atlas and lineage study applications.

Dec 28, 2016

Zymo Research Sample Collection Devices

Zymo Research has launched five new sample collection devices featuring the company's DNA/RNA Shield storage reagent, which preserves the integrity and expression profiles of samples including cells, tissues, blood, plasma, serum, saliva, urine, and feces at ambient temperatures for extended periods.

The new collection devices are: DNA/RNA Shield Swab Collection Tube, ideal for mouth, nose, throat, and environmental samples; DNA/RNA Shield Blood Collection Tube, ideal for gene expression analysis, miRNA analysis, and blood-borne pathogen detection; DNA/RNA Shield Fecal Collection Tube, which can be used for miRNA analysis, pathogen detection, gene expression, and microbiomic analysis; and DNA/RNA Shield Lysis Tubes for tissues and microbes.

Dec 22, 2016

GenBank 217

GenBank 217 is now available via ftp from the National Center for Biotechnology Information. Uncompressed flatfiles in this release require 809 gigabytes for sequence files only. The ASN.1 data requires approximately 671 GB.

Dec 21, 2016

Invitae Pediatric, Neurological, and Rare Disease Test Expansion

Invitae has launched 42 new and 19 expanded genetic test panels as part of the company's pediatric, neurological, and rare disease offerings. The new offerings allow clinicians to gain information on 183 genes with clinical and diagnostic significance. The expanded offerings include comprehensive testing for epilepsy and epilepsy-related disorders; an expansion of panel testing for developmental disorders, overgrowth syndromes, skeletal disorders, and RASopathies/Noonan spectrum disorders; incorporation of the latest genetic findings for ciliopathies; and consolidation of clinical areas, enabling customers to order a broader set of tests that are relevant for the patient.

Pages

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.

A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.