New Products

Mar 02, 2017

Agilent GenetiSure Dx Postnatal Assay

Agilent Technologies has launched the GenetiSure Dx Postnatal Assay. The assay uses the company's comparative genomic hybridization technology, which provides data on copy number variations and absence of heterozygosity. The test will help clinical labs implement cytogenetic testing, Agilent said.

Mar 02, 2017

Lexogen Quantitative RNA-Seq Service

Lexogen has launched its RNA-Seq service. It uses the company's QuantSeq technology to produce gene expression profiles. The library preparation procedure is automated and the workflow allows for a high degree of multiplexing, the company said. The service costs €248 per sample, which includes library preparation, lane mixing, sequencing, and all required quality controls for processing 48 samples concurrently. Customers are then sent a report that provides data analysis down to the differential gene expression. Further analyses are available upon request.

Mar 01, 2017

Magic-BLAST 1.2.0

Version 1.2.0 of the BLAST RNA-seq mapping tool, Magic-BLAST is now available. The new release allows researchers to handle multiple SRA accessions, offers improved splice site detection, and multi-threading performance. The update also fixes issues with macOS installation. The release are available here, and the executables are available here.

Mar 01, 2017

Courtagen Spotlight Genetic Tests for Neuromuscular Disorders

Courtagen Life Sciences has launched an expansion of its Spotlight test menu in neurology and endocrinology. The 10 new gene panels increase the company's selection of tests available for epilepsy, developmental delay, endocrinology, and mitochondrial disease. They primarily address neuromuscular disorders, such as congenital myasthenia, hereditary spastic paraplegia, congenital and limb-girdle muscular dystrophy, and myopathies, and one new endocrine disorder test for Bardet Biedl syndrome.

Mar 01, 2017

Zymo Discovery Series Nucleic Acid Kits

Zymo Research has launched its Discovery Series DNA and RNA purification kits.The new kits include reformatted versions of the company's eight most popular kits. Each kit contains enough components to process a maximum of 10 samples, and comes in 5- and 10-prep/reaction formats. The Discovery Series kits include the Zymoclean Gel DNA Recovery kit, DNA Clean & Concentrator -5 kit, ZymoBiomics DNA Miniprep kit, Quick-RNA MiniPrep Plus kit, EZ DNA Methylation-Lightning kit, ZymoPure Plasmid Miniprep kit, and Quick-DNA Miniprep Plus kit.

Mar 01, 2017

Invivoscribe CE-IVD LymphoTrack Dx Assays

Invivoscribe Technologies has launched three new CE-marked in vitro diagnostic assays for the company's Ion PGM Dx System. The new assays include an IGH, IGK, and TRG clonality assays to aid in the diagnosis of B-cell malignancies. When the IGH and IGK assays are used together, it's possible to detect clonality in a majority of B-cell malignancies with nearly 100 percent clinical sensitivity, the company said. Additionally, when all three assays are used together, it is possible to detect a least one clonal biomarker target in the vast majority of hematologic malignancies, the company said.

Feb 23, 2017

Aeon BDx Advantage Blood Diagnostic Testing Service

Authentidate Holding subsidiary Aeon Global Health has added the BDx Advantage Blood Diagnostic testing service to its portfolio. The service menu includes metabolic, hepatic, and renal function testing; advanced lipid profiles; and general chemistry and extensive hormone testing. All testing will be run through the company's Roche Cobas 6000 high-throughput chemistry analyzer, the company said.

Feb 23, 2017

Eurofins Genomics Oligonucleotide Synthesizer Platform

Eurofins Genomics has launched its new DNA synthesizer platform. The platform synthesizes EXTREmer oligonucleotides. The oligonucleotides are up to 200 bases long with a coupling efficiency of 99.5 percent or greater. The EXTREmers allow for the construction of genes with segments of low sequence variability that would be difficult to sequence with shorter oligonucleotides, the company said. They can also be used as a template for in vitro transcription of RNA molecules.

Feb 22, 2017

IDT Ultramer DNA and RNA Oligonucleotides

IDT has launched its Ultramer DNA and RNA oligonucleotides. The Ultramer DNA oligos are 45 to 200 nucleotides in length, available in single- or double-stranded format, and are provided deprotected and desalted. The Ultramer RNA oligos are long, single-stranded RNA of 60 to 120 nucleotides. Each oligo is assessed by mass spectrometry to verify sequence integrity using IDT's proprietary electrospray ionization method, the company said.

Feb 22, 2017

Vortex Biosciences VXT1 Liquid Biopsy System

NetScientific portfolio company Vortex Biosciences has launched the VTX1 Liquid Biopsy System, a fully automated benchtop for collecting intact circulating tumor cells (CTCs) that are shed by tumors. It uses the company's patented microfluidic technology to isolate CTCs directly from whole blood samples and direct them into containers for downstream analysis, the company said.

Feb 22, 2017

Repositive Autism Data Collection

Repositive has launched the Autism Data Collection, a database comprised of over 6,500 datasets from autism patients. The datasets were sourced from nine different data sources and include whole-exome sequencing data, microRNA data, and data on the role of the microbiome in autism. The whole-exome sequencing data makes up the largest portion of the database, and was generated through a partnership between Baylor College of Medicine and the Broad Institute of MIT and Harvard, the company said.

Feb 21, 2017

SeraCare Seraseq Fusion RNA Mix v2 and FFPE Fusion RNA Reference Material v2

SeraCare Life Sciences launched the Seraseq Fusion RNA Mix v2 and Seraseq FFPE Fusion RNA Reference Material v2. The highly multiplex mixes include 15 clinically actionable fusion RNA partners. Two formats are offered — purified nucleic acid and formalin-fixed, paraffin-embedded tissue slices. 

Feb 21, 2017

Horizon Discovery's Synthetic Plasma cfDNA Reference Standard

Horizon Discovery Group has launched a new tool called the HDx cell-free DNA Reference Standard in Synthetic Plasma. According to the company, the new reference set addresses challenges in extracting DNA for liquid biopsy testing, helps to ensure that an assay is not over or under loaded, and allows users to better control variation in their tests. The set contains eight cancer-relevant mutations including BRAF, EGFR, KRAS, NRAS, and PIK3CA at 5 percent, 1 percent, and 0.1 percent allelic frequencies. Because the reference is engineered in plasma, mimicking actual human material, users can gain better understanding of assay performance from extraction and quantification through to analysis and informatics, Horizon added.

Feb 17, 2017

Swift Biosciences Accel-NGS XL Library Prep Kit

Swift Biosciences has launched the Accel-NGS XL Library Prep Kit for whole-genome sequencing on Pacific Biosciences instruments. The kit has a four-hour workflow and has been optimized for PacBio's single molecule real-time sequencing technology.

Feb 16, 2017

Cofactor Genomics Pinnacle Assay

Cofactor Genomics has launched Pinnacle, an RNA-based oncology assay which provides insights into a patient's cancer profile. The assay reports on both aberrant oncology-relevant gene expression and known cancer gene fusions detected in the tumor sample. It uses the company's software to compare each patient's cancer expression profile to Cofactor's database of thousands of expression profiles from the same cancer type, the company said. Pinnacle is currently approved for use with formalin-fixed, paraffin-embedded tumor tissue.

Feb 16, 2017

MagBio Genomics Blood STASIS 21-CcfDNA Tube

MagBio Genomics has launched the Blood STASIS 21-ccfDNA tube for venous whole blood collection and room temperature stabilization of circulating cell-free DNA. The tube is a direct draw whole blood collection system that contains a proprietary reagent that prevents post-collection release of genomic DNA from white blood cells. It allows room temperature transport and storage of blood for 21 days, and epithelial cell for 8 days, the company said.

Feb 16, 2017

Immucor MIA FORA NGS HLA Typing Assay

Immucor has launched the MIA FORA NGS FLX HLA Typing assay that provides comprehensive coverage of up to 11 HLA genes. The assay provides whole gene coverage all major HLA gene regions, including whole gene coverage for HLA-A, B, C, DPA1, DQA1, and DQB1; all exons and introns for HLA-DRB1, 3, 4, 5 except partial coverage for exon 6 and intron 1; and all exons and introns between exons  and 4 for HLA-DPB1. Clinicians can prep and sequence the sample in less than 24 hours, and have the option to choose between a 5, 6, 9, or 11 gene kit for testing.

Feb 16, 2017

SoftGenetics GeneMarker HTS Software

SoftGenetics has launched GeneMarker HTS software for analysis of the mitochondrial genome in both forensic and clinical research applications. The software provides a streamlined workflow for forensic and medical research mitochondrial NDa data analysis from next-generation sequencing systems such as the Illumina and Ion Torrent platforms. It aligns data to a reference, and optimizes detection of INDELS and discovering variants, including SNPs, INDELS, and heteroplasmy. The software also includes quick export to EMPOP, user management, audit trail capabilities, synchronized comparison of multiple samples, customizable viewing, and reporting to protect health information.

Feb 16, 2017

Genomenon Mastermind

Genomenon has launched Mastermind, an analytic and data visualization tool that accelerates gene and variant curation. The software mines millions of medical publications and delivers a comprehensive knowledge base of disease-gene-variant relationships curated from primary medical literature, organized into clinical categories, and prioritized by the strength of evidence, the company said. Mastermind has reviewed literature and found associated variants for all the genes from Thermo Fisher Scientific's Ion AmpliSeq comprehensive cancer panel; Illumina's TruSight Tumor 170 solid tumor cancer panel; Thermo Fisher's and Fulgent's hereditary cancer panels; and Thermo Fisher's, Illumina's, and Fulgent's cardiomyopathy panels.

Feb 14, 2017

PreventionGenetics PGxome

PreventionGenetics launched the newly expanded PGxome whole-exome sequencing tests. In addition to diagnostic whole-exome testing, the PGxome Health Screen is now available to healthy individuals who want to learn more about their carrier status for recessive disorders and susceptibility to adult onset illnesses. Pharmacogenomic testing will be added to the PGxome test menu soon, PreventionGenetics said. 

Feb 10, 2017

Cole-Parmer DNA Prep Kit by Arcis Biotechnology

Cole-Parmer has launched the DNA Prep Kit by Arcis Biotechnology. The Arcis kit can be used for DNA and/or RNA extractions from fluids, such as blood, and requires as little as 30 µl of sample. It uses a two-step workflow that prepares samples in three minutes with high yields. The product is ideal for PCR, real-time PCR, isothermal amplification, sequencing, genetic profiling, and forensic studies, and can be easily integrated into automated processes, the company said. 

Feb 09, 2017

Courtagen Spotlight Gene Panels for Neurology and Endocrinology

Courtagen Life Sciences has launched 17 new gene panels in its Spotlight line of tests, expanding its menu in neurology, endocrinology, and other disease areas. The new tests include several pain-related panels, such as migraine, neuropathic pain, and abdominal pain. They also include endocrinology-related panels for hyper/hypoglycemia (MODY+), hyperparathyroidism, and pituitary hormone deficiency, and new neurology panels for neuromuscular disorders such as periodic paralysis, dystonia, and rhabdomyolysis.

Feb 09, 2017

EntroGen Sample Quality Assessment Products

EntroGen has launched two sample quality assessment products, the DNA Fragmentation Quantification assay and the Library Quantification kit for Illumina. Both products determine quantity and quality of DNA samples prior to running downstream qPCR. The DNA Fragmentation Quantification assay evaluates the amount of amplifiable DNA in a sample, and detects the presence of PCR inhibitors. The Library Quantification kit for Illumina utilizes primers designed to bind to P5 and P7 adaptor oligos for the detection of properly adaptor-indexed libraries for NGS sequencing on any Illumina instrument. 

Feb 08, 2017

Bioline JetSeq DNA Library Preparation Kits

Meridian Bioscience subsidiary, Bioline, has launched its JetSeq DNA Library Preparation kits. The kits, developed in collaboration with Oxford Gene Technology, use pre-optimized buffers to provide maximum reaction efficiency and highest conversion rates, the company said. They also  use a combination of end repair and A-tailing followed by direct ligation of customer supplied adapters to reduce clean-up steps, and improve yield and quality of sequence ready libraries. The kits come in PCR and PCR-free versions.

Feb 03, 2017

GenTegra Ahlstrom GenSaver Card

GenTegra and Ahlstrom have launched the Ahlstrom GenSaver collection card for dried blood spots. The card, which is available in several formats, protects DNA in dried blood spots for more than 20 years without freezing. It combines special paper and GenTegra-DNA Active Chemical Protection, a chemical matrix that helps preserve DNA in the dry state.  

Pages

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.

A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.