New Products

Nov 20, 2014

Bio-Rad CFX Automation System II for Real-Time PCR

Bio-Rad Laboratories has launched the CFX Automation System II, a robotic plate handler that automates high-throughput real-time PCR for all Bio-Rad CFX Real-Time PCR Detection Systems. The automation system can operate one or two CFX PCR systems with a single plate handler, and is easily integrated with LIMS, Bio-Rad said. The system also features software that enables the integration of Bio-Rad's PrimePCR assays.

Nov 19, 2014

New England Biolabs' WarmStart RTx Reverse Transcriptase

New England Biolabs has released a novel, thermostable reverse transcriptase called WarmStart RTx Reverse Transcriptase that is designed for use in reverse transcription loop-mediated isothermal amplification, RT-PCR, and other applications for detecting low-quantities of target RNA from complex sample matrices. WarmStart RTx is reversibly inhibited at room temperature, and is activated when warmed above 40° C, which enables researchers to set up their reactions at room temperature with no background reverse transciptase activity.

Nov 17, 2014

Personal Genome Diagnostics' CancerSelect Enterprise Solution

Personal Genome Diagnostics has launched its CancerSelect Enterprise Solution for labs with next-generation sequencing capabilities that aim to conduct advanced cancer genetic testing for research applications.  CancerSelect ES provides a turnkey solution that includes the firm's CancerSelect gene panels, proprietary bioinformatics software, staff training, ongoing technical support, report generation, and panel updates. The two PGDx CancerSelect panels detect alterations in 88 and 203 well-characterized genes that are of high biologic importance in cancer, and were selected for their relevance to cancer-related drug targets and pathways, according to the company.

Nov 17, 2014

Personal Genome Diagnostics' CancerSelect Targeted Gene Panel

Personal Genome Diagnostics has launched its CancerSelect targeted gene panel through its MyPersonalGenome service. The CancerSelect panel detects alterations in 88 well-characterized genes that include all targets of currently available or investigational cancer treatment options, the firm said. PGDx analyzes the CancerSelect genes using next-generation sequencing at extremely high coverage and proprietary PGDx technologies to identify a comprehensive list of genetic alterations, including point mutations, copy number alterations, and genetic rearrangements.

Nov 16, 2014

Maxis II Q-TOF

Bruker this week introduced its Maxis II Q-TOF mass spec, which, the company said, is the new flagship in its TOF mass spec line.

The instrument offers 80,000 resolution at UPLC acquisition speeds as well as a high mass option for intact protein work such as biopharma characterization and electron transfer dissociation capability.

Nov 16, 2014

AdvanceBio RP-mAB Column

Agilent has introduced its AdvanceBio RP-mAB column for separation of monoclonal antibodies. The reversed-phase column comes in three chemistries, C8, C4 and unique diphenyl, and is 3.5 µm, 450Å superficially porous, and stable to 600 bar, the company said.

 
Nov 16, 2014

qPCR Design Lab

Biosearch Technologies this week introduced qPCR Design Lab, a comprehensive website for assay design, oligo analysis, webinars, and references.

Visitors to qPCR Design Lab can quickly perform common dilution and resuspension calculations with an oligo toolbox or determine physical properties of an oligo with the OligoSpec calculator. Users can also visualize combinations of fluorophore absorption and emission spectra with the Spectral Overlay Tool for multiplexed qPCR, and can obtain reporter dye and quencher recommendations specific to their real-time PCR instruments.

Nov 16, 2014

New AccuSpan Panels

SeraCare Life Sciences this week introduced seven new AccuSpan molecular linearity panels for the detection of adenovirus, varicella-zoster virus, JC virus, herpes simplex viruses 1 and 2, Epstein-Barr virus, and BK virus.

The new panels help assay developers challenge their transplant assays from extraction phase through amplification. Each panel comprises one negative, one low positive, one medium positive, and one high positive sample. The panels come in a ready-to-use format with target concentrations covering the dynamic range of most molecular assays, SeraCare said.

Nov 16, 2014

PowerMag Blood DNA/RNA Isolation Kit

Mo Bio Laboratories has launched the PowerMag Blood DNA/RNA Isolation Kit.

The new kit is designed for automated purification of nucleic acids from blood samples using the Thermo Fisher Scientific KingFisher automated processing system and other similar automation platforms. The kits work with all types of blood samples, including fresh and frozen whole blood, buffy coat, plasma, and stabilized blood. They also feature the company's ClearMag magnetic particle technology, which captures DNA and RNA without binding common blood-derived PCR inhibitors, Mo Bio said.

Nov 16, 2014

Omicia Adds Phevor to Opal

Omicia is integrating Phevor, the Phenotype Driven Variant Ontological Re-ranking tool, into its Opal product, including Opal Clinical. Phevor is an algorithm co-developed by Omicia and researchers at the University of Utah to identify disease-relevant variants in genomic sequences.

Nov 16, 2014

SeqCap RNA Target Enrichment System

Roche has launched its SeqCap RNA Target Enrichment System for RNA-seq applications. The offering includes lncRNA design and custom enrichment options. The kit enables researchers to design customized targeted RNA-seq panels that focus on a subset of genes or transcripts.

Nov 16, 2014

PippinHT

Sage Science has launched PippinHT, a high-throughput DNA sizing platform for next-generation sequencing workflows. The platform incorporates the company’s sizing technology and increases throughput to 24 samples per run, compared to a maximum of five with Pippin Prep or BluePippin, and shortens run times by about 50 percent.

Nov 16, 2014

GeneFriends

A University of Liverpool team has expanded GeneFriends, an online functional genomics tool, to include an RNA-seq-based co-expression map of genes and transcripts not present in its existing microarray-based co-expression maps.

Nov 16, 2014

Swift Biosciences' TP53 Panel

Swift Biosciences has launched an early access program for its next-generation sequencing-based TP53 Panel that covers all coding exons of the gene. The panel uses Swift's Accel-NGS Amplicon Panel technology and runs on Illumina's sequencing instruments. In addition, it is planning another panel using the Accel-NGS Amplicon technology that will target over 200 clinically relevant cancer mutations.

 
Nov 16, 2014

Almac's P53 Mutation Assay

Almac Group has launched a CLIA validated next-gen sequencing assay for P53 mutations. The test can be run on formalin-fixed paraffin-embedded samples and covers all coding regions and upstream regulatory regions of P53.

Nov 16, 2014

Archer Assay Designer

Enzymatics has launched Archer Assay Designer, a software platform to design custom primer panels to generate target-enriched libraries in order to identify gene fusions through next-gen sequencing. The software allows the user to search for genes and exons of interest.

Nov 16, 2014

Rapid Heme Panel

The Dana-Farber Cancer Institute and the Brigham and Women's Cancer Center have a launched Rapid Heme Panel, a next-gen sequencing-based panel that analyzes alterations in 95 genes that are frequently associated with leukemias and myeloid disorders. The test has a turnaround time of five business days.

Nov 16, 2014

WuXi PharmaTech's Genome Center

WuXi PharmaTech's Genome Center is now offering analysis services from NextCode Health, a bioinformatics company in Cambridge, Mass., which will provide population-scale genome analysis. NextCode will work with the WuXi Genome Center to process sequence data from WuXi's customers and produce a report discussing the medical implications.

Nov 16, 2014

Chromosome Analysis Suite 3.0

Affymetrix has added a new feature to version 3 .0 of its Chromosome Analysis Suite software, a tool that enables researchers analyze and visualize the functional impact of copy number changes on gene expression in cancer samples. The company's newly added concurrent molecular analysis profiling capability lets cancer researchers combine whole-genome copy number data with gene expression profiles and explore the functional impact of copy number alterations.

Nov 16, 2014

MacVector 13.5

MacVector has released MacVector 13.5, the latest version of its sequence analysis software. This release makes comparing large sequences faster and improves handling of NGS data. Specifically, it has a new interface and includes enhancements to the Align to Reference and Align to Folder functions among other updates.

Nov 16, 2014

qbase+ 3.0

BioGazelle has released version 3.0 of its qbase+ qPCR data-analysis software. Features in this release include a data analysis wizard that simplifies the process of analyzing qPCR data. It provides step-by-step directions for importing data, annotating runs, doing data quality control, validating reference gene stability, performing normalization, and more.

Nov 16, 2014

RefSeq 68

RefSeq 68 is now available from the National Center for Biotechnology Information via ftp.

The release has over 66 million records describing 46,968,574 proteins, 9,069,704 RNAs, and sequences from 49,312 distinct NCBI TaxIDs.

Nov 16, 2014

Cytoscape 3.2

Cytoscape 3.2 is available here.

New features include faster startup, session loading, and drawing of large networks; the ability to display a node as a chart; and safer internal data handling of multi-threaded apps among others.

Nov 16, 2014

DiscoveryQuant 3.0

AB Sciex has released DiscoveryQuant 3.0 software, a new version of its ADME solution for high-throughput drug discovery. The release speeds up the method development process using existing database information, automates on-column optimization, and easily analyzed and processes multiple samples at the same time among other capabilities

Nov 16, 2014

BioCyc

SRI International has updated its BioCyc database collection to include a mobile application for remote access, as well as additional repositories that support researchers studying genomes and metabolic pathways.

With these additions, version 18.5 of the resource adds access to 5,500 genomes and information about connections between sequences and biological function. It also links the sequences of microbial genomes to curated metabolic pathways among other updates.

Pages

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.

A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.