New Products

Apr 07, 2015

Proove Opioid Response

Proove Biosciences has launched Proove Opioid Response, a clinical laboratory test to predict a patient's response to opioid pain medications. The test provides physicians information about which opioids a patient is likely to respond to and assesses 49 genetic variations for information about safety and effectiveness in five specific opioids — hydrocodone, oxycodone, morphine, tramadol, and hydromorphone.

Apr 01, 2015

GRCh37 update for Ensembl 79

The European Bioinformatics Institute has added new information for the GRCh37 human reference assembly to Ensembl 79. The updated information includes variation data for human from dbSNP build 142, imported genotypes from the thrid phase of the 1000 Genomes project, and a new regulatory build among other updates.

Mar 31, 2015

Igenbio's Ergo 2.0

Igenbio has released Ergo 2.0, the latest version of its informatics toolkit for use in comparative genomics projects. The company's platform provides a curated genomic pathway database and tools that let users capture, query, and visualize data from sequenced genomes. Users can assign functions to genes; integrate genes and pathways; and identify unkown or mischaracterized genes and gene products among other capabilities.

Mar 31, 2015

Multiplicom Somatic 2 MASTR Plus Kit

Multiplicom has released the Somatic 2 MASTR Plus kit for the detection of actionable somatic mutations in the EGFR, ERBB2, PIK3CA, PIK3R1, and PTEN genes, extending its somatic MASTR product line that already covers KRAS, NRAS, BRAF, cKIT, and PDGFRA. The somatic MASTR products are designed for amplification of formalin-fixed, paraffin-embedded tissue-derived DNA. The kit requires only a limited amount of DNA and all mutations are analyzed in a single sequencing run. The quality of the DNA extracted from the FFPE tissue and the amount required per test can best be determined using Multiplicom's add-on QC Plex test, the company said.

Mar 31, 2015

Exiqon's miRNA NGS Service

Exiqon has launched its next-generation sequencing services for miRNAs present in blood serum and plasma. The new services provide a complete sample-to-answer solution, including the biological interpretation of customer results. Customers also can teleconference with Exiqon's experts in NGS and RNA to go over the results, it said.

Mar 31, 2015

Medicinal Genomics' SenSATIVAx

Medicinal Genomics, a subsidiary of Courtagen Life Sciences, has launched the SenSATIVAx Plant/Microbial DNA Purification Kit, a DNA sample preparation kit that uses magnetic microparticles to isolate and purify both plant and microbial DNA from homogenized cannabis samples. The kit provides 30-minute DNA recovery in a scalable and automated format for microbial safety testing and research into cannabis plant genetics.

Mar 31, 2015

Kapa Biosystems' Probe Force qPCR Kit

Kapa Biosystems has launched the Kapa Probe Force qPCR Kit. The kit contains inhibitor-resistant DNA polymerase and master mix to improve amplification and quantification directly from crude samples. It is compatible with TaqMan and other fluorogenic probe chemistries, and can shorten workflows by enabling low-cost extraction methods from blood, tissue, and plant specimens.

Mar 27, 2015

OpenHelix Bioinformatics Training Services

OpenHelix, a divsion of Bio-IT World that provides open-access bioinformatics resources, has launched a new website as well as expanded subscriber services for academic and commercial research institutions. 

OpenHelix offers over 100 tutorials on popular bioinformatics and genomics tools. The redesigned website support more concise and accurate navigation and easiser access to popular tutorial suites among other updates. 

Mar 26, 2015

Pathway Genomics' ColoTrue and LynchSyndromeTrue

Pathway Genomics announced it has launched ColoTrue, a comprehensive panel that combines next-generation sequencing with deletion/duplication analysis to detect pathogenic variants in 15 high-risk colorectal cancer susceptibility genes. Pathway has also launched a smaller five-gene panel, LynchSyndromeTrue, which tests genes associated with Lynch syndrome, the most common form of hereditary colon cancer.

Mar 25, 2015

Agena Bioscience's LungFUSION Panel

Agena Bioscience has released its LungFUSION Panel for rapid and sensitive identification of oncogenic ALK, RET, and ROS1 gene fusions in non-small cell lung cancer tumors. The panel contains built-in controls to simultaneously assess RNA quality, report DNA contamination, and determine the relative amount of lung tissue present in the sample. It runs on the firm's MassArray platform, which detects genetic variation directly by end-point PCR and label-free mass spectrometry.

Mar 25, 2015

Cypher Genomics' Mantis

Cypher Genomics has released a new software update to automate the interpretation of sequencing data from cancer genomes. With the update, Cypher's Mantis technology will now provide rapid insight into how different genetic variants may impact cancer progression and therapeutic effectiveness, the company said. The update will also provide a summary of somatic and germline variants for single nucleotide variants and small indels, as well as resolve difficult-to-classify variants of unknown significance.

Mar 25, 2015

Courtagen's LysoSEEK

Courtagen Life Sciences has released LysoSEEK, a genetic test focused on early identification of genes associated with potentially treatable lysosomal storage disorders.

The LysoSEEK panel provides extensive genetic analysis and clinical interpretation of data generated by the complete sequencing of 94 genes associated with close to 60 metabolic disorders. The test seeks out enzymatic deficiencies in the lysosomes, and examines additional genes useful for differential diagnosis, Courtagen said.

Mar 20, 2015

Cartagenia's BenchLab NGS

Cartagenia has upgraded its Bench Lab NGS software to enable laboratories to implement the recently released ACMG/AMP recommendations for standards and guidelines on the interpretation of sequence variants. 

According to the company, Bench Lab NGS now includes a framework for labeling and scoring variants based on the criteria and levels of evidence in the ACMG paper. Labs can also put together a variant assessment pipeline that represents their own implementation of the ACMG guidelines.

Mar 20, 2015

Sequenom's HerediT Universal

Sequenom Laboratories, a wholly owned subsidiary of Sequenom, has launched the HerediT Universal carrier screening test, expanding the firm's reach into the universal carrier screening market. The HerediT Universal screens for more than 250 genetic diseases by analyzing over 2,000 genetic mutations and can be performed preconception or at any time during pregnancy, the firm said. The test is being offered in collaboration with Recombine, a clinical genetic testing firm.

Mar 19, 2015

Promega PowerQuant System

Promega has announced the release of the PowerQuant System, an STR analysis product to determine total human DNA concentration in a sample, quantify male DNA, assess integrity, and discover possible PCR inhibitors. The probe-based system uses four targets and five dyes to ensure that the DNA detected in the quantification steps will result in a usable STR profile. The system can be also used in tandem with the PowerQuant Analysis Tool program.

Mar 17, 2015

Genection's MyAML NGS Assay

Genection has launched MyAML, a CLIA-validated next-generation sequencing assay that identifies clinically actionable, pathogenic, and potentially pathogenic mutations in 194 genes associated with acute myeloid leukemia. The panel identifies single-nucleotide variants, insertion-deletion variants, and the entire range of structural variants, including partial tandem duplications and translocations, Genection said.

Mar 17, 2015

Ensembl 79

Ensembl release 79 is available here.

This release includes an update to the ensembl-Havana GENCODE gene set as well as new assembly patches, a RefSeq-to-ensembl model comparison, and an interactive gene gain/loss tree view, among other improvements.

Mar 13, 2015

Pressure BioSciences' PCT-HD system

Pressure BioSciences has commercially released its PCT-HD system, which combines its micro-Pestle consumable with an enhanced Barocycler NEP2320 instrument. "This combination enables faster, less cumbersome, and higher quality homogenization, extraction, and digestion of proteins," the firm said in a statement. The system was developed in collaboration with Ruedi Aebersold and Tiannan Guo, researchers with ETH Zurich's Institute of Molecular Systems Biology.

Pressure Bio noted that researchers will give talks at next week's US Human Proteomic Organization meeting on the advantages of using the PCT-HD System for biomarker discovery.

Mar 11, 2015

Bioline Isolate II Nucleic Acid Purification Kits

Bioline, a subsidiary of Meridian Bioscience, has launched five kits as part of its Isolate II nucleic acid purification product portfolio. The new kits are: Isolate II miRNA, Plant miRNA, Biofluids RNA, RNA/DNA/Protein, and FFPE RNA/DNA.

The new kits are based on silica membrane spin column technology and optimized buffer chemistry; feature simple bind-wash-elute steps; and are designed for rapid, phenol-free isolation of high-quality nucleic acids, including miRNA, even from difficult-to-process samples, Bioline said. The new kits also efficiently purify high-quality large RNA species such as mRNA, the company said.

Mar 11, 2015

GoldenHelix's VarSeq

Golden Helix has released  VarSeq 1.1.1, the latest version of its software for annotating and filtering variants obtained from NGS pipelines.

This version of the software includes a phenotype gene ranking application called PhoRank, a phenotype driven variant ontological re-ranking tool that is modeled on the Phevor algorithm. It calculates gene scores that can be used to rank and filter variants and it prioritizes variants based on the gene's relevance to the observed phenotype.

Mar 09, 2015

Thermo Scientific Sample Manager

Thermo Fisher Scientific has released Thermo Scientific SampleManager, a new laboratory information management system.

The LIMS solution includes visualization capabilities, tools for managing data and laboratory activities, and it can be integrated with existing enterprise-level infrastructure. Other features include intuitive dashboards, enhanced statistical quality control tools, and more.

Mar 09, 2015

Enlis Genome Research 1.8

Enlis Genomics has released Enlis Genome Research 1.8. This release includes a new phenotype explorer tool that lets users search for keywords that match diseases and traits and also see specific positions and variations that are associated with that phenotype. The tool comes preloaded with known variation for over 6,000 phenotypes. Also included in this release are several major annotation updates and new options for vcf filtering during import.

Mar 09, 2015

Genedata Expressionist

Genedata has released Expressionist 9.0, the latest version of its software for analyzing mass spectrometry data.

This release of the software is designed to be compliant with GxP guidelines and includes audit logging and electronic signatures. It also allows for the implemenation of standard operating procedures for workflow processes and enables the formal approval of reports among other updates.

Mar 05, 2015

Illumina's TruSight HLA

Illumina has launched its TruSight HLA, a sequencing-based solution for accurate HLA typing across thousands of known and novel HLA alleles. The kit includes the TruSight HLA Sequencing Panel, a single assay for ultra-high resolution analysis of all the key genes within the major histocompatibility complex, reagents for preparing and sequencing DNA libraries, and optimized data analysis with software from Conexio Genomics.

Mar 03, 2015

ArcherDx's Software

ArcherDx has launched new versions of its Archer suite of software programs. 

Archer Analysis 3.1 now supports automated sequence analysis, which inmproves turnaround times and enables researchers to call genomic alterations faster than previously possible. Archer Assay Designer 2.0 supports the creation of multiplex gene fusion assays by modifying existing, optimized catalog panels. And Archer Quiver, a database of gene fusion information, has been updated to include the latest information from COSMIC, PubMed, and other repositories.


In a survey, about half of Canadian government scientists say they still feel as though they cannot speak freely, ScienceInsider reports.

Clinicians in China are moving ahead with a number of CRISPR trials, NPR reports, as the US embarks on its first.

The Atlantic reports that biohacker Josiah Zayner regrets injecting himself with the CRISPR gene-editing tool on stage.

In Nature this week: genomic approaches applied to study Neolithic and Bronze Age Europeans, and more.