Close Menu

New Products

Jun 17, 2019

Qiagen Microbial Insights AR

Qiagen has launched Microbial Insights AR (QMI-AR), an integrated genomic database that provides curated, single-point entry access to four of the world's largest knowledgebases on antimicrobial resistance. Specifically, it integrates the Comprehensive Antibiotic Resistance Database (CARD), ResFinder, a National Institutes of Health AMRFinder database of resistance genes, as well as the ARG-ANNOT database of peptide markers. According to Qiagen, the database complements ARESdb, a comprehensive, regularly updated genomic knowledgebase on clinically relevant antibiotic resistance strains that the firm has made available to the global research community through a partnership with Ares-Genetics, a Curetis subsidiary. Qiagen said that it will offer QMI-AR through the CLC Microbial Genomics Module, an extension to the CLC Genomics Workbench bioinformatics software.

Jun 17, 2019

GeneCast RUO Kits

South Korea-based liquid biopsy firm GeneCast has launched a set of research-use-only kits for BRAF, EGFR, and JAK2 mutation detection. The firm claims technical sensitivity for the BRAF assay as low as 0.0001 percent, and for the EGFR and JAK2 kits of 0.01 percent. The products use the company's ADPS quantitative PCR method, and the firm said it is working on gaining approval to offer the products for clinical use, filing a PMA submission with the US Food and Drug Administration, for the EGFR assay for example. GeneCast plans to launch additional RUO kits for KRAS, NRAS, PIK3CA, pTERT, IDH1, and IDH2 by the end of this year.

Jun 17, 2019

Twist Bioscience Mouse Core Exome Panel

Twist Bioscience has launched the Mouse Core Exome Panel for target enrichment in next-generation sequencing. The comprehensive panel for research use is built from the most current databases.

Jun 17, 2019

Paragon Genomics CleanPlex NGS Panels

Paragon Genomics has launched a series of CleanPlex products for MGI sequencers. The firm now offers its CleanPlex for MGI Ready-to-Use NGS panels, which can be used for both MGI's OncoZoom Cancer Hotspot Panel and MGI's BRCA1 and BRCA2 Panel. Paragon also offers its CleanPlex for MGI Custom NGS panels, which allow researchers to build customized assays to address specific needs. The firm noted that its support staff will take custom orders, developing and delivering panels that are completely compatible with MGISEQ sequencers. In addition, Paragon is offering validated automation protocols ensuring that CleanPlex for MGI assays can work with the MGISP-960 Automated Sample Preparation System to produce the same results performed if done manually. 

Jun 14, 2019

BGI Whole Exome Sequencing Service

BGI Genomics has launched a clinical research whole exome sequencing service called BGI-Xome, which incorporates clinical interpretation services from UK-based Congenica. BGI will perform WES at its service laboratories, while interpretation will be completed by clinical scientists using the Congenica clinical decision support platform. According to BGI, Congenica's Interpretation platform will allow its service to provide a "gold-standard" and effective solution that eliminates the risk of users missing or misidentifying disease-linked mutations. 

Jun 13, 2019

Oxford Gene Technology SureSeq NGS Library Prep Kit

Oxford Gene Technology has released a new SureSeq library preparation kit for hybridization-based target capture in next-generation sequencing. According to the firm, the kit offers a streamlined protocol with enrichment by hybridization with a ready-to-use hybridization and wash buffer. It also reduces manual handling steps to increase reliability and throughput. The firm also said that the kit lowers duplication rates, leading to more accurate calling and more even coverage.

Jun 12, 2019

Patients Choice Laboratories UTI+ Test

Patients Choice Laboratories has launched the UTI+ molecular test for urinary tract infections. The Indianapolis-based company said the new test is part of its goal to be a full-service lab. It added that its gene- and molecular-based technologies provides uropathogenic and antibiotic resistance testing results within six hours after specimen receipt compared to up to three days with urinalysis by culturing. 

Jun 11, 2019

Genestack Omics Data Manager

Genestack has introduced Omics Data Manager, a system for cataloguing, curating, indexing, searching, and sharing multi-omics data. Omics Data Manager can serve as centralized repository for enterprises looking to implement the FAIR (Findable, Accessible, Interoperable, and Reusable) principles for biomedical data management. Omics Data Manager can be integrated into laboratory information management systems and third-party, upstream data analysis platforms, according to Cambridge, UK-based Genestack. 

Jun 07, 2019

Thermo Fisher Scientific Orbitrap Exploris 480, Orbitrap Eclipse Tribrid Instruments and Mass Spectrometry Software

Thermo Fisher Scientific launched a number of mass spectrometry instruments and software this week.

The Thermo Scientific Orbitrap Exploris 480 mass spectrometer enables more rigorous high-throughput protein identification, quantitation, and structural characterization. It has a smaller footprint than previous instrument versions and maintains high resolution, mass accuracy, and spectral quality.

The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer has improved sensitivity over previous generations and is better able to characterize and quantify complex biomolecules and biological systems.

Both new instruments can be combined with the Thermo Scientific FAIMS Pro interface, a differential ion mobility device that improves selectivity and increases productivity across a range of proteomics workflows.

The new Thermo Scientific TraceFinder Software 5.0 offers quicker and easier access to information from Thermo Scientific TSQ Quadrupole and Q Exactive Hybrid Quadrupole-Orbitrap mass spectrometry platforms. In addition, the Thermo Scientific Almanac web-based application enables users to remotely access instruments to monitor their run status and data acquisition.

Jun 06, 2019

Arbor Biosciences MyNGS Guides MitoDeplete Kits

Arbor Biosciences, a division of Chiral Technologies, has launched MyNGS Guides MitoDeplete Kits as part of its catalog of guide RNA pools for targeted sequencing applications. This new depletion system combines Arbor's massively parallel, high-fidelity oligo synthesis platform with Cas enzymes for efficiently targeting unwanted molecules from NGS libraries. In-stock MitoDeplete catalog kits have been designed and validated for human and mouse applications, and the company can design and synthesize kits for other custom species on demand.

MitoDeplete kits are designed for use on any NGS library containing a significant percentage of mitochondrial DNA molecules, such as ATAC-Seq libraries. CRISPR-based depletion with MitoDeplete delivers up to a 95 percent reduction in mtDNA-derived molecules in a single-step process. The human and mouse kits are available for immediate shipment in an eight-reaction kit size. Kits for custom species can be produced on request through collaboration with one of the product scientists at Arbor.

Jun 06, 2019

Sciex TripleTOF 6600+ LC-MS/MS System

Sciex has launched the TripleTOF 6600+ LC-MS/MS System with ScanningSwath Acquisition alongside high-performance data processing with OneOmics in Sciex Cloud. The latest entry in Sciex's TripleTOF portfolio, the new platform incorporates simplified low-flow source technology to deliver accessible, sensitive and robust quantification; while multiple software-enabled improvements increase robustness and maximize system uptime, Sciex said.

Other features include OptiFlow Turbo V Source for all low-flow applications, with flow rates of 100 nL/min to 200 L/min; up to 100 Hz MS/MS scan speeds; and Analyst TF Software 1.8, which features scheduled ionization and target TIC function to give users temporal control over the number of ions entering the systems.

Sciex also introduced ScanningSwath Acquisition to be hosted on the system. This feature immortalizes samples by creating a digital data record of all detectable analytes, capturing more detail about potential markers than its predecessor, Sciex said.

Jun 04, 2019

Illumina VeriSeq NIPT Solution v2

Illumina has launched the VeriSeq NIPT Solution v2, a CE-IVD, next-generation sequencing-based approach to noninvasive prenatal testing. The new version expands the range of chromosomal and sub-chromosomal conditions associated with birth defects that laboratories can screen for. The assay provides information about fetal chromosomal status as early as 10 weeks of gestation using a single maternal blood draw, and provides an option to screen for aneuploidy in all autosomes, chromosomes X & Y, and partial deletions and duplications greater than 7 Mb across the genome. It is available in Europe and South Africa; registration is pending in Australia, Israel, and New Zealand.

Jun 04, 2019

Synthego Gene Knockout Kit v2

Synthego has launched its Gene Knockout Kit v2. The kit is based on a multi-guide strategy that employs up to three modified single guide RNAs targeting the same gene. These sgRNAs are spatially coordinated to reliably induce a fragment deletion of 21 or more base pairs. This intentional edit occurs at high frequency, increasing the probability of gene knockout, the company said. Each kit includes one tube of chemically modified multi-guide sgRNA, designed to target any human protein-coding gene, and the purchase of a kit includes free access to Synthego's ICE CRISPR Analysis Tool.

Jun 04, 2019

Tempus Integrated Molecular Evaluation (TIME) Trial

During this week's American Society of Clinical Oncology meeting, Tempus introduced Tempus Integrated Molecular Evaluation (TIME) Trial. This service features a proprietary technology platform that analyzes molecular and clinical data on cancer patients in real time to match people to clinical trials. TIME Trial only sends patients to prequalified academic and community cancer centers so those who qualify can enroll right away. 

Jun 03, 2019

Day Zero Diagnostics epiXact WGS Sequencing Service

Day Zero Diagnostics (DZD) has commercially launched its epiXact whole genome sequencing and analysis service for hospital-acquired infection outbreak investigations. According to DZD, the service allows hospital infection control teams to determine the relationships between infections during a suspected outbreak. The firm said that the service can provide results in two to three days and can help hospital confidently and quickly decide how to perform interventions for patient safety. 

Jun 03, 2019

NRGene DeNovoMax

NRGene has launched DeNovoMax, a product for assembling reference-level genomes for use in breeding and agriculture. 

DeNovoMax is a version of NRGene's legacy DeNovoMagic platform that maximizes efficiency by using a leaner library setup. DeNovoMax is designed to meet the needs of professional breeders and will be offered for the most popular homozygote species including wheat, tobacco, tomato, pepper, cotton, corn, soybean, and sunflower.

May 31, 2019

Bruker TimsTOF FleX, IntelliSlides, SCiLS Lab 2020

Bruker announced several new mass spectrometry products and workflows to be launched at the American Society for Mass Spectrometry Conference, held June 2-6 in Atlanta.

First, the company introduced the TimsTOF FleX mass spectrometer, which includes a software-switchable MALDI source adapted to the ESI TimsTOF Pro platform. This new combined ESI/MALDI capability enables spatially resolved omics, which the company calls SpatialOMx, on a single instrument. TimsTOF FleX comes with Bruker's prorietary 10-kHz SmartBeam 3D laser with true pixel fidelity for rapid, label-free MALDI imaging at high spatial resolution while preserving the 4D proteomics and phenomics sensitivity of the TimsTOF Pro in ESI mode. The approach enables researchers to gain insights into spatial molecular distributions in tissues from MALDI imaging, and to guide 4D omics molecular expression studies, for example on proteins, low-level cancer antigen peptides, lipids, glycans, metabolites, or xenobiotics, which cannot be observed by traditional staining or labelling techniques, the company said.

Bruker also launched IntelliSlides specifically designed to automate TimsTOF FleX workflows. The IntelliSlides come pre-inscribed with software-readable 'teach marks' on the conductive surface to indicate where to place the tissue sample, a bar code and tracking number. The company also released SCiLS Lab 2020 MALDI imaging software, now integrated with MetaboScape5.0 to provide automated annotations of lipids and metabolites in tissue molecular images in SpatialOMx.

May 31, 2019

Sema4 Centrellis Health Intelligence Platform

Sema4 has launched several genomic testing services and digital tools as part of its Centrellis Health Intelligence Platform. According to the firm, the tools provide a comprehensive approach to track a patient's cancer, and are based on 250x tumor coverage and 100x normal coverage across all genes.

The research use only tools include: Patient Journey, which provides an interactive timeline visualization of the patient's health journey and offers services such as diagnoses, treatments, and molecular profiles; Cohort Builder, which offers the ability to define groups of patients according to specific parameters such has stage, histology, and treatments to understand treatment patterns, identify appropriate clinical trials, and allow data-driven decisions about patient care; and VONC, which is an automated variant curation platform using a wide array of databases to support curation of genetic information at scale with clinical evidence to recommend therapy decisions.

Using 100 million reads, the services provide clinical data about a wide range of genomic variants, gene fusion and alternative splicing, tumor mutational burden, and microsatellite instability, the firm said. Researchers can perform the services using fresh frozen, paraffin-embedded, bone marrow, blood, or saliva samples.

May 29, 2019

Loop Genomics Microbiome Sequencing Sample Prep Kits

Loop Genomics has launched four new sample preparation kits for use on Illumina sequencers to help identify the presence and relative abundance of organisms in the human microbiome. 

The kits include: a low biomass phased V1-V9 full-length 16S kit with picogram input amounts and zero human DNA background; a phased 18S-ITS1-ITS2 long-read solution for fungal Mycobiome profiling that interrogates an approximately 2.5-kb contiguous region of the genome; a low biomass version of the fungal profiling kit; and a 16S read-cloud kit offering V1-V9 coverage without V1-V9 phasing.

May 29, 2019

Fluidigm Advanta Solid Tumor NGS Library Prep Assay

Fluidigm has launched the Advanta Solid Tumor NGS Library Prep Assay for the simultaneous detection of somatic variants across 53 solid tumor genes using a microfluidic library prep workflow. The assay was developed for use with the company's Juno system which automates the target enrichment of single-nucleotide variations, indels, and copy number variations for subsequent analysis on Illumina sequencing platforms. The assay comes with a new Juno LP 8.8.6 microfluidic cartridge that enables users to easily process up to six different panels simultaneously with 10-fold lower sample input. Users can also add new cancer markers to the Advanta panel using Fluidigm D3 assay design services, the company said.

May 24, 2019

PreOmics PreON

PreOmics has launched its PreON protein sample preparation platform. According to the company's website, PreON processes 4 to 12 samples in less than three hours and uses a plug-and-play method selection that streamlines protein sample processing for mass spectrometry-based protein analysis. The benchtop system also features an onboard heated shaker, automated swing-out centrifuge, and automated pipetting, and is designed to eliminate both manual processing steps and errors.

May 23, 2019

Philip Morris International GladiaTox

Philip Morris International (PMI) has launched GladiaTox, an open-source informatics product for high-content screening data in biomedical research. According to PMI, GladiaTox allows "robust and efficient storage, processing, and reporting of HCS data, in line with the landmark 21st Century Toxicology program." The firm's platform is an evolution of the ToxCast Pipeline created for the US Environmental Protection Agency. The solution can analyze disparate types of HCS data in an integrated fashion and supports the "3S" approach to biological understanding – "systematic, systemic, and systems," which looks at organisms in their entirety rather than specific organs in isolation. PMI developed GladiaTox in collaboration with Filer Consulting.

May 23, 2019

MGI Single-Cell RNA Sequencing Solution

BGI subsidiary MGI has begun marketing a product solution that allows users of BGI and MGI sequencing platforms to perform single-cell RNA sequencing (scRNA-seq) with 10x Genomics' technology. The solution includes the MGIEasy Universal Library Conversion Kit, a new product, as well as the 10x Genomics Chromium Controller and Single-Cell RNA Solutions. Researchers from the UK and Australia recently tested BGI's sequencing technology for scRNA-seq with 10x Genomics' platform.

May 17, 2019

New England Biolabs Monarch Genomic DNA Purification Kit

New England Biolabs has launched the Monarch Genomic DNA Purification Kit for high-yield purification of high-molecular-weight DNA fragments (peak size greater than 50 kb), making it ideal for use upstream of long-read sequencing platforms. The inclusion of RNase A, optimized protocols, and buffer chemistry enable researchers to prevent RNA contamination (RNA levels are generally less than 1 percent) and address a wide variety of sample types without having to purchase any specialized kits, NEB said.

May 14, 2019

Primerdesign Genesig q32

Primerdesign, the molecular business of Novacyt, has launched a next-generation molecular testing instrument called Genesig q32. The new qPCR instrument is larger than the firm's Genesig q16 instrument and provides customers with a faster, higher throughput solution for using Novacyt's genesig real-time PCR kits. The q32 provides test results within 60 minutes using Genesig kits, processing up to 32 patient samples in tube or strip format with fluorescence detection technologies.

Pages

New research shows that scientists need to do a better job of including a wider diversity of African genomes in their analyses, STAT says.

A new paper in Science shows that men are still winning a large majority of the most sought-after NIH grants.

Nature Research and the Estée Lauder Companies are awarding efforts to encourage girls to pursue careers in the STEM fields.

In Science this week: beneficial genetic variants inherited from archaic Neanderthal and Denisovan hominins, and more.