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Xcell NGS System for Cell-Based Assays

Xcell Biosciences said this week that the company will unveil its Avatar system at the Molecular Medicine Tri-Conference next week in San Francisco. The new system enables a new generation of cell-based assays by allowing for complete control of key physiological conditions found in the microenvironments of cells, the company said. It also overcomes the limitation of traditional cell culture to generate results that exhibit the phenotypic, genomic, and proteomic characteristics of the native sample, the company said.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.