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Waters ProteinWorks Digest Kits

Waters has launched a new line of ProteinWorks digest kits that simplify, accelerate, and standardize the LC-MS quantification of proteins via the surrogate peptide approach. The kits contain pre-measured, lot-traceable reagents, a 96-tube flexible sample collection module, and easy-to-follow protocols. This enables reproducible, fast digestion and accurate, sensitive protein quantification in both immunopurified and whole, non-immunopurified plasma and serum samples. The ProteinWorks product portfolio includes an optional, optimized µElution SPE kit and protocol designed to increase assay sensitivity, reduce matrix interferences, and improve LC-MS system robustness. 

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.