Skip to main content
Premium Trial:

Request an Annual Quote

Varigen Biosciences Biosynthetic Gene Cluster Custom Cloning Service

Varigen Biosciences has launched custom cloning of bacterial or fungal biosynthetic gene clusters of up to 100 kb in length. The company said that its DNAtrap technology enables it to deliver intact gene cluster clones from microbes in 10 days. Varigen has cloned 32 PKS, NRPS, and other pathways of interest with high fidelity from dozens of bacterial and fungal strains. In addition, for already-cloned pathways the firm offers shuttling to its new heterologous BGC expression vector.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.