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Varigen Biosciences Biosynthetic Gene Cluster Custom Cloning Service

Varigen Biosciences has launched custom cloning of bacterial or fungal biosynthetic gene clusters of up to 100 kb in length. The company said that its DNAtrap technology enables it to deliver intact gene cluster clones from microbes in 10 days. Varigen has cloned 32 PKS, NRPS, and other pathways of interest with high fidelity from dozens of bacterial and fungal strains. In addition, for already-cloned pathways the firm offers shuttling to its new heterologous BGC expression vector.

The Scan

Booster Push

New data shows a decline in SARS-CoV-2 vaccine efficacy over time, which the New York Times says Pfizer is using to argue its case for a booster, even as the lower efficacy remains high.

With Help from Mr. Fluffington, PurrhD

Cats could make good study animals for genetic research, the University of Missouri's Leslie Lyons tells the Atlantic.

Man Charged With Threatening to Harm Fauci, Collins

The Hill reports that Thomas Patrick Connally, Jr., was charged with making threats against federal officials.

Nature Papers Present Approach to Find Natural Products, Method to ID Cancer Driver Mutations, More

In Nature this week: combination of cryogenic electron microscopy with genome mining helps uncover natural products, driver mutations in cancer, and more.