Twist Bioscience NGS Methylation Detection System
Twist Bioscience has launched the Twist NGS Sequencing Methylation Detection system, a sample preparation and target enrichment solution for identifying methylated regions in the human genome.
The system uses EM-seq from New England Biolabs, an enzyme-based alternative to traditional bisulfite sequencing methods that enables preparation of enzymatically converted libraries. The system also includes Twist methylation enhancer, universal blocker and FastHyb, and custom methylation panels that include DNA probes to capture all four potential sequences at a given site: methylated, unmethylated, sense and antisense.
The products can be used in liquid biopsy cancer analysis and epigenetic studies.