TwinStrand Biosciences Duplex Sequencing Technology

TwinStrand Biosciences this week launched TwinStrand Duplex Sequencing Technology kits at the Advances in Genome Biology and Technology meeting. Duplex Sequencing is a biochemistry- and software-based enhancement to existing next-generation sequencing platforms that improves accuracy by more than 10,000-fold, the company said. Optimized chemistry enables users to complete library preparation in one to two days, while cloud-based informatics provide the ability to fully process, analyze, interpret, and graphically present multi-terabyte raw sequencing data. The company will offer its technology initially for two research applications: detection of minimal residual disease in acute myeloid leukemia patients, and a multi-species genetic toxicology assay for rapid identification of carcinogenic chemicals in preclinical testing, as well as detection of patients who have been environmentally exposed.