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TriLink Biotechnologies CleanTag Primer Sets

TriLink Biotechnologies has introduced two new primer sets for its CleanTag kit. The Ion Torrent Convert barcode primer sets allow small RNA library preparation on Thermo Fisher Scientific's sequencing platform. According to TriLink, CleanTag includes modified adapters that block adapter-dimer formation. The firm said that CleanTag uses automated, bead-based separation to allow a simplified, cleaner workflow, retaining high sensitivity, and the ability to work with low-abundance RNA input as well as at the single-cell level. Primers in each index set for Ion Torrent include the RT primer, 12 indexed forward-PCR primers, and a reverse-PCR primer. 

The Scan

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.

Study Looks at Parent Uncertainties After Children's Severe Combined Immunodeficiency Diagnoses

A qualitative study in EJHG looks at personal, practical, scientific, and existential uncertainties in parents as their children go through SCID diagnoses, treatment, and post-treatment stages.

Antimicrobial Resistance Study Highlights Key Protein Domains

By screening diverse versions of an outer membrane porin protein in Vibrio cholerae, researchers in PLOS Genetics flagged protein domain regions influencing antimicrobial resistance.

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.