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Thermo Fisher Scientific QuantStudio 5 Real-Time PCR System

Thermo Fisher Scientific has launched the Applied Biosystems QuantStudio 5 Real-Time PCR system for human identification. The system is designed to deliver efficient performance with a smaller footprint and lower annual maintenance costs, the company said. It has been optimized with the new HID Real-Time PCR Analysis Software v1.3, which allows researcher to perform data analysis with a virtual standard curve feature to minimize variation and reduce costs associated with using standards on every plate. The software also includes quantification and short tandem repeat setup features.

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.