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Thermo Fisher Scientific Applied Biosystems Precision ID GlobalFiler NGS STR Panel v2, Converge Software 2.0

Thermo Fisher Scientific has released the Applied Biosystems Precision ID GlobalFiler NGS STR Panel v2 and Converge Software 2.0 for forensic research. The products are designed to retrieve more information from mixed, degraded, or limited DNA samples. The new panel works with the Ion Chef system for library and template preparation and the Ion S5 and Ion S5 XL sequencing systems. It targets expanded core loci from the Combined DNA Index System (CODIS), with additional multi-allelic STR markers, including Penta D and Penta E, and sex determination markers. The new software module is required to generate profiles from the panel. It provides information on length-based STR allele calls, sequence-based repeat motifs, known SNPs in flanking regions, and isometric heterozygotes. 

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.