Logo

Thermo Fisher Scientific Applied Biosystems Precision ID GlobalFiler NGS STR Panel v2, Converge Software 2.0

Jul 20, 2017

Thermo Fisher Scientific has released the Applied Biosystems Precision ID GlobalFiler NGS STR Panel v2 and Converge Software 2.0 for forensic research. The products are designed to retrieve more information from mixed, degraded, or limited DNA samples. The new panel works with the Ion Chef system for library and template preparation and the Ion S5 and Ion S5 XL sequencing systems. It targets expanded core loci from the Combined DNA Index System (CODIS), with additional multi-allelic STR markers, including Penta D and Penta E, and sex determination markers. The new software module is required to generate profiles from the panel. It provides information on length-based STR allele calls, sequence-based repeat motifs, known SNPs in flanking regions, and isometric heterozygotes. 

Breaking News
The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.