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Takara Bio In-Fusion Cloning Primer Design Tool

Takara Bio subsidiary Takara Bio USA has launched the In-Fusion Cloning Primer Design Tool. The free online tool is powered by TeselaGen Biotechnology software, and provides researchers with a method to seamlessly join together linear fragments of DNA in a single, 15-minute reaction. It can support a wide range of cloning applications, including multi-fragment cloning, mutagenesis, and general cloning.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.