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Synthego Online CRISPR Tools

Synthego has released online CRISPR tools that make more than 100,000 genomes accessible for gene knockout guide design. The tools include a guide designer, a design validator, and the ability to order CRISPR guide RNA. Researchers can select a desired gene of interest from a curated list of genomes representing more than 9,000 species. The Synthego tool then uses several built-in algorithms to instantly generate guide designs and recommendations for the most efficient guides with low off-target effects and highest likelihood to knock out the function of a gene, the firm said. Additional features include the ability to validate, share, and purchase synthetic single guide RNA. The new tools are free to use and available at

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.