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Synthego Inference of CRISPR Edits Software

Synthego has launched a new tool named Inference of CRISPR Edits, or ICE. This CRISPR analysis software features rapid, reproducible batch processing of Sanger data. It's also free to use and open source, according to the company. Featuring an easy-to-use interface, ICE provides insertion and deletion percentage, indel contributions, and total discordance against wild-type sequence data for up to hundreds of samples at a time, the company said.

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.