Synthego Gene Knockout Kit v2

Synthego has launched its Gene Knockout Kit v2. The kit is based on a multi-guide strategy that employs up to three modified single guide RNAs targeting the same gene. These sgRNAs are spatially coordinated to reliably induce a fragment deletion of 21 or more base pairs. This intentional edit occurs at high frequency, increasing the probability of gene knockout, the company said. Each kit includes one tube of chemically modified multi-guide sgRNA, designed to target any human protein-coding gene, and the purchase of a kit includes free access to Synthego's ICE CRISPR Analysis Tool.