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Synthego Gene Knockout Kit v2

Synthego has launched its Gene Knockout Kit v2. The kit is based on a multi-guide strategy that employs up to three modified single guide RNAs targeting the same gene. These sgRNAs are spatially coordinated to reliably induce a fragment deletion of 21 or more base pairs. This intentional edit occurs at high frequency, increasing the probability of gene knockout, the company said. Each kit includes one tube of chemically modified multi-guide sgRNA, designed to target any human protein-coding gene, and the purchase of a kit includes free access to Synthego's ICE CRISPR Analysis Tool.

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.