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Synthego Engineered Cells Portfolio

Synthego has launched its Engineered Cells product portfolio, giving customers immediate access to Knockout Clone and Pool, and Advanced Cells. The Knockout Cell Pools provide researchers the ability to purchase engineered cell populations with a first-ever guaranteed knockout frenquency of 50 percent or greater with a single click. These engineered cells will be delivered in as few as four weeks. The high knockout frequency allows researchers to use the pools directly in many assays or efficiently generate clonal populations.

Knockout Cell Clones give researchers the most complete access to CRISPR with no additional steps required. These engineered cell clones are 100 percent sequence verified to contain the gene of interest knocked out and are delivered in as few as eight weeks.

Advanced Cells are optimal for researchers working on more complex gene editing projects, the company said. Researchers can use Synthego's expertise to design, execute, and analyze genome editing projects that go beyond single-gene knockouts, including knock-ins (protein modifications, protein tagging, transgene insertions) and editing complex primary cells and stem cells.

The Scan

Review of Approval Process

Stat News reports the Department for Health and Human Services' Office of the Inspector General is to investigate FDA's approval of Biogen's Alzheimer's disease drug.

Not Quite Right

A new analysis has found hundreds of studies with incorrect nucleotide sequences reported in their methods, according to Nature News.

CRISPR and mRNA Together

Time magazine reports on the use of mRNA to deliver CRISPR machinery.

Nature Papers Present Smartphone Platform for DNA Diagnosis of Malaria, Mouse Lines for Epigenomic Editing

In Nature this week: a low-cost tool to detect infectious diseases like malaria, and more.