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Synthego CRISPRevolution Gene Knockout Kit

Synthego has launched its new CRISPRevolution Gene Knockout Kit (GKO) for all CRISPR researchers, including those developing emerging therapeutic modalities with increasing genome engineering demands such as CAR-T immunotherapy and treatment of monogenic diseases. The CRISPRevolution GKO includes four top-scoring guides from Synthego's CRISPR Design Tool, provided as high efficiency chemically modified synthetic sgRNAs, SpCas9 protein, and control reagents to optimize transfection protocols. This kit has an easy-to-use experimental workflow, and comes with a money-back guarantee on 50 percent or better editing in any human cell type for research use.

The Scan

Booster Push

New data shows a decline in SARS-CoV-2 vaccine efficacy over time, which the New York Times says Pfizer is using to argue its case for a booster, even as the lower efficacy remains high.

With Help from Mr. Fluffington, PurrhD

Cats could make good study animals for genetic research, the University of Missouri's Leslie Lyons tells the Atlantic.

Man Charged With Threatening to Harm Fauci, Collins

The Hill reports that Thomas Patrick Connally, Jr., was charged with making threats against federal officials.

Nature Papers Present Approach to Find Natural Products, Method to ID Cancer Driver Mutations, More

In Nature this week: combination of cryogenic electron microscopy with genome mining helps uncover natural products, driver mutations in cancer, and more.