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Sygnis TruePrime WGA Kit

Sygnis has launched the TruePrime WGA kit for whole-genome amplification of entire genomes from various sample types.

The TruePrime technology is based on multiple displacement amplification (MDA) of DNA or RNA species from a variety of samples. TruePrime combines Sygnis' recently discovered DNA primase TthPrimPol with its Phi29 polymerase, and does not require the use of any synthetic random primers. The new kit eliminates common artifacts linked to the use of oligonucleotides, reduces amplification bias, is insensitive to external DNA contaminations, and has a high reproducibility, the company said. These features make it attractive for researchers who are working with limited sample volumes but do not need to obtain DNA from individual cells, Sygnis added.

The TruePrime WGA kit is available globally through distributors as well as through Sygnis' TruePrime online shop. It is available in 25- or 100-reaction formats.

Sygnis also previously launched a TruePrime kit for amplification of DNA from single cells.