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Sygnis TruePrime Apoptotic Cell-Free DNA Amplification Kit

Sygnis has launched the TruePrime apoptotic cell-free DNA amplification kit under the Expedeon brand. The kit enables accurate DNA amplification using cell-free DNA from plasma, serum, urine, cerebrospinal fluid, and other bodily fluids. The kit uses a multiple displacement amplification method to overcome common limitations of cell-free DNA analysis of such fluids, Sygnis said, adding it provides users with "excellent sensitivity, error-free amplification in hih yields, and a streamlined workflow for reduced hands-on time." 

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.