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Swift Biosciences Accel-NGS Unique Dual Indexing Kit

Swift Biosciences has announced the release of its Accel-NGS Unique Dual Indexing Kit. Developed in a set of 96 dual indices for both i7 and i5 positions, the indexing kits improve misassignment rates to less than a percent and enable multiple applications including whole-genome sequencing, as well as whole-exome and methylation analysis. In addition, Swift's kits allow a scalable workflow for low-frequency somatic variant discovery, formalin-fixed paraffin-embedded analysis, microbial detection in human samples, and cell-free DNA analysis. The kits are compatible with any Illumina sequencing platform.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.