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Swift Biosciences Accel Amplicon CFTR Panel and Accel-NGS XL Library Prep Kit

Swift Biosciences has launched the Accel Amplicon CFTR panel, which detects a wide range of variants and mutants in all exonic and select intronic regions of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. It produces sequence libraries in two hours, allows the user to process three to four times more libraries per day, and requires as little as 10 nanograms of sample input from either whole blood, dried blood spots, saliva, or buccal swabs.

The company has also launched the Accel-NGS XL Library Prep kit, which optimizes library preparation, particularly for the PacBio's Single Molecule, Real-Time SMRT sequencing. The kit provides longer sequencing reads with a single-tube workflow.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.