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SoftGenetics MaSTR Probabilistic Mixture Analysis Software

SoftGenetics has released a new probabalistic mixture analysis software product called MaSTR. Designed according to probabalistic guidelines set by the Organization of Scientific Area Committees for Forensic Science and the Scientific Working Group on DNA Analysis Methods, MaSTR is meant to provide transparency to help forensic professionals better describe DNA findings in courtrooms. State College, Pennsylvania-based SoftGenetics said that it is making the MaSTR analysis code available to users on a confidential basis only.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.