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SGI-DNA's Gibson Assembly Site-Directed Mutagenesis Kit

SGI-DNA has launched the Gibson Assembly Site-Directed Mutagenesis Kit which allows researchers to efficiently and accurately perform site-directed mutageneisis on DNA fragments. The Gibson Assembly method has become a mainstay in many synthetic biology laboratories and has attracted interest from both the academic and commercial life sciences community due to its ease of use, robustness, and flexibility, said SGI-DNA in a statement. Starting with a circular or a linear DNA template up to 25 kilobases in length, the kit enables researchers to introduce up to five site-directed mutations in a single round with efficiencies of 95 percent and 55 percent, respectively.

The Scan

Review of Approval Process

Stat News reports the Department for Health and Human Services' Office of the Inspector General is to investigate FDA's approval of Biogen's Alzheimer's disease drug.

Not Quite Right

A new analysis has found hundreds of studies with incorrect nucleotide sequences reported in their methods, according to Nature News.

CRISPR and mRNA Together

Time magazine reports on the use of mRNA to deliver CRISPR machinery.

Nature Papers Present Smartphone Platform for DNA Diagnosis of Malaria, Mouse Lines for Epigenomic Editing

In Nature this week: a low-cost tool to detect infectious diseases like malaria, and more.