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Sera Prognostics PreTRM Test

Sera Prognostics has announced a program for limited commercial access to PreTRM, a proteomic biomarker blood test designed to provide an early, objective, and individualized assessment of a woman's risk of preterm birth. The test will be made available in limited locations in the US, beginning with selected clinical sites that participated in the Proteomic Assessment of Preterm Risk study. All testing will be conducted at Sera's CLIA-certified laboratory in response to orders from women's healthcare professionals. Following the early access outreach to physicians in selected markets this fall, Sera is planning for a wider national PreTRM rollout in 2016, the company said in a statement.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.