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Sequencher 5.4

Gene Codes has released Sequencher 5.4, a new version of its next-generation sequence data analysis software. The release includes new RNA-seq analysis features such as a customized graphic interfaces for the Cufflinks software suite, a tool to generate html reports and provide 11 different metrics on users' raw NGS data, and access to SAMtools, among other updates. The company is offering version 5.4 as a free upgrade for clients that are enrolled in its maintenance program and 30-day free access for new users interested in testing the software.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.