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SeqOnce Biosciences RhinoSeq Rapid DNA Library Preparation Kit

Mar 21, 2019

SeqOnce Biosciences has launched its RhinoSeq DNA Library Preparation Kit for next-generation sequencing sample preparation. The firm said that the five tube kit contains preformatted master mixes for a simple, fast, and stable workflow. The tool generates a temporary structure that creates sequence-specific single stranded overhangs for sequencing adaptor litigation. When combined with fragmentation and PCR steps, the kit's 12 minute library construction uses a single master-mix that produces libraries in less than 45 minutes. SeqOnce said that the kit produces best results using a DNA input between 5 to 100ng.

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Aug 16, 2019

Integrated DNA Technologies oPools Oligo Pools

Integrated DNA Technologies has launched its oPools Oligo Pools, ready-to-use pools of high-quality DNA oligonucleotides. According to the Coralville, Iowa-based firm, the pools contain customized, single-stranded DNA sequences between 40 and 350 nucleotides in length. Because the pools are delivered in picomoles, researchers do not need to perform any pre-amplification or other pre-work before using the pool. IDT said that oPools' low error rate of less than 1 in 2,000 nucleotides, coupled with high per-oligo yields, allow researchers to immediately proceed into their downstream workflows including CRIPSR library construction, protein screening, and gene assembly.   

Aug 15, 2019

Loop Genomics LoopSeq Bacterial Genome Sequencing Kit and Services

Loop Genomics has launched a new sample preparation kit and service for de novo bacterial genome assembly using synthetic long reads on Illumina sequencers.

The LoopSeq Bacterial Genome Sequencing kit leverages the firm's chemistry and computational pipeline to create reads thousands of base pairs long, providing high-quality assemblies with fewer total contigs, higher N50 values, and fewer misassemblies.

San Jose, California-based Loop Genomics said the kit is plug-and-play and can easily replace existing sample preparation kits for bacterial genome sequencing experiments, using Loop's software for data analysis.

Aug 13, 2019

Dovetail Genomics Omni-C Assay

Dovetail Genomics has launched the Omni-C, a new assay based on the Hi-C method for chromosome conformation capture.

Scotts Valley, California-based Dovetail said it designed the assay for ease of use and improved reproducibility. The firm claims the assay offers better coverage compared to standard Hi-C approaches, by using an endonuclease, rather than restriction enzymes, to digest cross-linked chromatin.

Traditional restriction enzyme-based Hi-C approaches generate data only near the restriction enzyme sites, resulting in gaps of information. By using an endonuclease, Omni-C enables coverage of a significant portion of the genome that does not contain these restriction sites, estimated to be around 20 percent in human genomes. 

Applications for Omni-C include structural genetic variant detection and generating genome assemblies. 

Aug 09, 2019

Streck ARM-D Kits; RNA Complete BCT

Streck this week launched three new real-time PCR antibiotic resistance kits for research use only. The kits cover MCR, expanded OXA, and TEM/SHV/GES to detect variants of resistance genes considered by the US Centers for Disease Control.

Streck also introduced RNA Complete BCT, a direct-draw whole-blood collection tube containing a specially designed reagent which maintains the draw-time concentration of extracellular vesicles such as exosomes for up to 7 days at room temperature storage.

Aug 08, 2019

Novogene NovoPM 2.0 Cancer Panel

Chula Vista, California-based Novogene has launched its NovoPM 2.0 Cancer Panel, a next-generation sequencing panel that analyzes 484 solid tumor-related genes and introns in 43 genes. According to the firm, the test can detect four types of genomic abnormalities (single nucleotide variation, insertions/deletions, copy number variation, and fusions), and features bioinformatics software including three algorithms specific for guiding cancer immunotherapy decision making.

Aug 08, 2019

ChunLab TrueBac ID

Korean bioinformatics firm ChunLab has launched TrueBac ID, a cloud-based platform that combines proprietary algorithms and a manually curated reference database for bacterial identification targeting more than 12,000 species. The system can provide a full identification report within 30 minutes after a user uploads a genome assembly or raw shotgun sequencing data as a FASTQ file. The report provides fully resolved taxonomic classification, antimicrobial resistance genes, and virulence genes to facilitate correct diagnosis and appropriate therapy. In a recently published study, TrueBac ID was able to accurately identify 34 of 36 clinical isolates (94.4 percent) that were not identified using three commercially available MALDI-TOF MS systems. ChunLab said that it is providing the service for free to all users until the end of 2019 with certain restrictions. In 2020, the company plans to add functions such as strain typing to the platform.

Aug 02, 2019

Twist Bioscience Long Oligonucleotides

San Francisco-based Twist Bioscience has launched its long oligonucleotides product line. According to the firm, the synthetic nucleotides can be upto 300 bases and will increase the success and productivity of biological research. While adding bases normally introduces the risk of error, Twist said it has developed a proprietary way to make oligos with an error rate as low as 1:1500 nucleotides.

Jul 31, 2019

Mesa Biotech RSV

San Diego, California-based molecular diagnostics developer Mesa Biotech has launched a respiratory syncytial virus test on its sample-to-answer point-of-care PCR system, the Acula. The RSV test is the second test on the system, which also runs an influenza A/B test and is exclusively marketed in the US by Sekisui under the Silaris brand. It was cleared by the US Food and Drug Administration and CLIA-waived last year for diagnostic use in both children and adults.

Jul 29, 2019

GridIon Mk1

Oxford Nanopore Technologies has launched GridIon Mk1, an upgrade to the GridIon X5 sequencing platform that will start shipping this week. It contains more powerful GPU technology, specifically a Nvidia Volta GV100 card, so basecalling now only requires 10 percent of the GPU resource. In addition, power requirements have been simplified, which increases the stability of the platform.

Jul 23, 2019

BioDot Rainmaker

Irvine, California-based BioDot has launched its Rainmaker picoliter volume printing platform. According to the liquid handling company, Rainmaker allows researchers to use up to 24 independent tips to dispense volumes ranging from 20 pL to several nLs at high speed. BioDot said the tool's programmable drop size and precision controls allow users to shrink assays to improve performance and reduce costs, while optimizing for rheology or surface characteristics. 

Jul 22, 2019

Clear Labs Clear Safety Listeria, Environmental Mapping Testing

Menlo Park, California-based Clear Labs has launched new Listeria testing and environmental mapping capabilities on its Clear Safety next generation sequencing platform.

According to Clear Labs, Clear Safety now catalogs the genetic "fingerprint" of a Listeria sample and compares it to the fingerprints of Listeria previously encountered within a company. The platform can now detect, speciate, and characterize up to seven Listeria species ( monocytogenes, grayi, innocua, ivanovii marthii, seeligeri, and welshimeri) in a single analysis.

Clear Labs also noted that researchers can use the platform's similarity analysis to distinguish resident from transient subtypes of Listeria in the food manufacturing environment, which groups samples containing Listeria with matching fingerprints and tags them with metadata including location, date, and time. The firm's environmental mapping tool then overlays Listeria contamination on a facility map, allowing the team to track the flow of particular subtypes of Listeria through a facility over time. 

Jul 18, 2019

Menarini Silicon Biosystems VRNxT Volume Reduction Tool

Italy-based Menarini Silicon Biosystems has launched its new VRNxT automated volume reduction instrument, which removes manual sample reduction steps in cellular biology workflows. The sample prep firm said that the instrument reduces pipetting steps by using rotational motion to reduce hands-on time up to 90 percent and eliminate operator variability. The system can simultaneously process up to four samples and reduces sample volume to about 12.5 μL in 25 seconds and approximately 2 μL in about eight seconds. Menarini claims the tool will add precision and accuracy to rare-cell and single-cell analysis, minimizing the loss of samples and increasing workflow throughput. While the system has been developed to standardize Menarini's DEPArray's workflow, the firm said that researchers can use the tool for broader applications in volume reduction.

Jul 17, 2019

3M STEC Tests

3M has introduced two genetic assays for food safety testing that detect Shiga toxin-producing E. coli. The assays are compatible with the St. Paul, Minnesota-based firm's loop-mediated isothermal amplification (LAMP) instrument, the 3M Molecular Detection System.

The 3M Molecular Detection Assay 2 - STEC Gene Screen (stx and eae) detects the genes for Shiga toxin types 1 and 2, in addition to the intimin gene that allows the bacteria to attach to intestinal cells. The firm's 3M Molecular Detection Assay 2 - STEC Gene Screen (stx) specifically detects Shiga toxin genes.

Jul 15, 2019

NanoString Alzheimer’s Disease Research Panels

Seattle-based NanoString Technologies has developed a set of new nCounter gene expression panels for use in Alzheimer's disease research, which it created and tested in collaboration with the MODEL-AD consortium. The two panels — one for use in mouse studies and another for human studies — measure the expression of 770 genes covering 30 modules discovered in a recent study of human brain tissue. The firm noted that both panels are available for purchase through its website.

Jul 12, 2019

HTG Molecular EdgeSeq Data Analytics Software Version 1.2

HTG Molecular Diagnostics has released an updated version of its HTG EdgeSeq Reveal data analytics software. According to the firm, the software allows customers to streamline sample analysis processed on the HTG EdgeSeq platform. The version 1.2 update contains improved functionality, offering data analysis from the firm's HTG EdgeSeq Precision Immuno-Oncology Panel, the HTG EdgeSeq Oncology Biomarker Panel, and the HTG EdgeSeq Mouse mRNA Tumor Response Panel.

The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.

Aug
29
Sponsored by
PerkinElmer

This webinar will outline how RUCDR Infinite Biologics, the world's largest university-based biorepository, has implemented workflows and processes to support precision medicine applications.

Sep
18
Sponsored by
Bionano Genomics

This webinar will outline how a team at Radboud University Medical Center is assessing ultra-long read optical mapping on the Bionano Saphyr system to replace classical cytogenetics approaches in routine testing and for the discovery of novel structural variants with potential scientific, prognostic, or therapeutic value that are missed by standard approaches.

Oct
01
Sponsored by
Thermo Fisher Scientific

This webinar will provide an overview of the sequencing capabilities of the Tumor Profiling Unit at the Institute for Cancer Research in London, with a focus on the lab's strategy for bringing in new genomics technologies.

Oct
03
Sponsored by
Agilent

This webinar will provide an overview of how an international reference laboratory has implemented an automated next-generation sequencing workflow with custom panels for analyzing cancer samples.