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SeqOnce Biosciences RhinoSeq Rapid DNA Library Preparation Kit

Mar 21, 2019

SeqOnce Biosciences has launched its RhinoSeq DNA Library Preparation Kit for next-generation sequencing sample preparation. The firm said that the five tube kit contains preformatted master mixes for a simple, fast, and stable workflow. The tool generates a temporary structure that creates sequence-specific single stranded overhangs for sequencing adaptor litigation. When combined with fragmentation and PCR steps, the kit's 12 minute library construction uses a single master-mix that produces libraries in less than 45 minutes. SeqOnce said that the kit produces best results using a DNA input between 5 to 100ng.

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Nov 14, 2019

Loop Genomics Long-Read PCR Amplicon Sequencing Kit, Service

Loop Genomics has launched a new amplicon library prep kit and service for generating synthetic long sequence reads from long PCR amplicons on Illumina sequencers. The kit can be used for PCR fragments up to 3 kb in size and the service can process orders for PCR fragments up to 6 kb long.

Nov 14, 2019

Grifols AlphaID,

Grifols has lunched the AlphaID, a cheek swab for use by doctors to screen patients with chronic obstructive pulmonary disease for alpha-1 antitrypsin deficiency, or Alpha-1, a rare, life-threatening genetic condition. Grifols said the swab is free "from ordering to results" and leverages a US Food and Drug Administration-approved genotyping assay to screen for the 14 most prevalently reported genetic mutations associated with Alpha-1, including the S, Z,F, and I alleles, as well as rare and null alleles. 

Nov 13, 2019

Personalis Whole Genome Sequencing Service

Personalis has launched a new whole genome sequencing service, extending its existing portfolio of comprehensive cancer 'omics tests, including targeted gene panels, exome, and transcriptome products. The company said that the new offering reflects its experience analyzing cancer samples across numerous biopharma oncology clinical trials, and takes advantage of "large-scale laboratory and data systems" developed as part of its WGS effort for the US Department of Veterans Affairs' Million Veteran Program.

Nov 08, 2019

Akoya Biosciences Motif PD-1/PD-L1 Panels

Akoya Biosciences has launched two multiplex immunofluorescence kits for profiling immuno-oncology biomarkers in the tumor microenvironment. The Motif PD-1/PD-L1 panels focus on PD-1 immune checkpoint blockade in lung cancer and melanoma. Each kit includes six immunofluorescence markers, plus nuclear counterstain, to capture the cellular interactions associated with PD-1/PD-L1 immune suppression. The kits are optimized for high-throughput staining on commonly used autostainers and rapid scanning on the Vectra Polaris multiplexed imaging system.

Nov 07, 2019

Ceres Nanosciences Nanotrap Virus Capture Kit

Ceres Nanosciences has launched the Nanotrap Virus Capture Kit, which concentrates whole virus particles from complex biological matrices resulting in high-quality input material for a range of downstream analytical methods such as multiplex nucleic acid, protein, and infectivity assays. The company said that it has data demonstrating the kit's compatibility with multiple commercial nucleic acid kits for influenza virus samples, as well as an application note demonstrating use of the technology to improve the detection of Zika virus in urine samples.

Nov 07, 2019

Ultivue UltiMapper Multiplex Immunofluorescence Kits

Ultivue has expanded its UltiMapper Multiplex Immunofluorescence Kit portfolio with a T-reg and MDSC kit. The UltiMapper I/O T-reg kit identifies regulatory T cells and cytotoxic T cells within the tumor context and allows for the phenotyping of activated double-positive T cells. The UltiMapper I/O MDSC kit enables the identification and characterization of myeloid-derived suppressor cells and allows researchers to differentiate M-MDSC from PMN-MDSC phenotypes. The new kits feature high-throughput whole-slide imaging using the same conventional IHC equipment and workflows as the previously released UltiMapper I/O PD-L1, UltiMapper I/O PD-1, UltiMapper I/O T-act, and UltiMapper I/O APC kits, the company said.

Nov 07, 2019

Qiagen QiaSeq Multimodal Panels

Qiagen has launched a new workflow, called QiaSeq Multimodal Panels, for the simultaneous preparation of DNA and RNA libraries for next-generation sequencing. The panels require an input as low as 10 nanograms of total nucleic acid and the workflow takes about nine hours. Both libraries are generated from the same sample and allow for the analysis of DNA variants, RNA fusions, and gene expression levels.

Nov 07, 2019

Lifebit Biotech CloudOS

Lifebit Biotech has introduced Lifebit CloudOS, a clorud-native, federated genomics operating system that supersedes the beta-release Lifebit Deploit from 2017. CloudOS works as a managed service of individual clouds or high-performance computing centers to support analysis of bioinformatics data across sites and institutions. The company said that this system automates analysis and the application of machine learning, removing a major barrier to precision medicine, population, genomics, drug discovery, and direct-to-consumer genetics progress. 

Nov 06, 2019

Genomenon Mastermind 2.0

Genomenon has introduced version 2.0 of its Mastermind genomic search engine. The new release features the ability to search genomic literature by phenotype to help with the diagnosis of rare and hereditary diseases. Genomenon said that this addition was the most requested improvement to the product from children's hospitals and genetic testing laboratories alike. 

Nov 05, 2019

Agena Bioscience VeriDose CYP2D6 CNV Panel

Agena Bioscience has launched the VeriDose CYP2D6 CNV panel to provide PGx testing programs with a more accurate and efficient way to analyze CYP2D6 copy number. The research-use-only panel quantifies CYP2D6 copy number even in the presence of CYP2D6/CYP2D7 hybrid alleles, which cannot be detected by commonly used PGx technologies, the company said. The panel can also be run alongside Agena's PGX genotyping panels.

Nov 05, 2019

Paragon Genomics CleanPlex CFTR Panel

Paragon Genomics this week introduced the CleanPlex CFTR Panel for cystic fibrosis testing. The panel uses the company's CleanPlex target enrichment technology for a multiplex PCR-based targeted sequencing assay to evaluate somatic and germline variants in the CFTR gene. It covers all exons of the gene and includes mutations recommended by the American College of Medical Genetics and Genomics.

Nov 05, 2019

Loop Genomics: Long Read Microbiome Sequencing Service

Loop Genomics has launched a new service for linked read microbiome sequencing for studies with large cohorts. For labs running at least 200 to 1,000 samples, Loop is offering 16S sequencing at a price between $38 and $20 per sample, depending on volume. Loop generates long reads using Illumina's short-read sequencing platform. The firm said it can deliver 40-fold lower error rates and can eliminate false positives, delivering species- and sometimes strain- level taxonomy.

Nov 01, 2019

Genome Medical's Genome Care Delivery

Genome Medical, a telegenomics technology and services company, has launched Genome Care Delivery, a cloud-based platform that provides hospitals, health systems, and employers virtual access to a nationwide network of clinical genetics specialists in order to expedite and facilitate the delivery of genetic expertise. The platform is initially focused on oncology and reproductive health, and is intended to deliver education, engagement, and access to genetic experts for virtual visits and provider-to-provider consults, as well as genetic wellness assessment and screening for population health management, the company said. Features include curated content, adaptive videos, webinars, online assessment tools, virtual care visits with genetic specialists, personalized recommendations regarding genetic testing, and clinical action plans based on genetic test results and medical management guidelines.

Oct 31, 2019

SeraCare SeraSeq TMB gDNA and FFPE Reference Materials

SeraCare Life Sciences has released what it says are the first available genomic DNA and formalin-fixed paraffin-embedded reference materials for tumor mutational burden measurement by next-generation sequencing assays. The company created the new materials as part of its work with the Friends of Cancer Research TMB harmonization working group and the International Quality Network for Pathology's TMB EQA Pilot Program.

Data generated from using the reference samples was presented by FOCR at the 2019 American Society of Clinical Oncology Meeting, and by IQN Path at the 2019 European Congress of Pathology, demonstrating their utility in harmonizing and standardizing measurements of TMB by different NGS assays.

In addition to the new SeraSeq TMB gDNA and FFPE materials available now, SeraCare said it can also create custom tissue and blood-based TMB reference materials through its VariantFlex custom reference material development platform.

Oct 31, 2019

Becton Dickinson Rhapsody Whole-Transcriptome Analysis Amplification Kit

Becton Dickinson has released a new solution for combined whole-transcriptome and protein analysis in single cells.

The BD Rhapsody Whole Transcriptome Analysis Amplification Kit enables unbiased 3'-based capture, amplification, and detection and is designed to work with BD's Rhapsody single-cell analysis system and AbSeq reagents. It is also optimized to work with BD's Single-Cell Multiplexing kit to improve efficiency.

The research-use-only kit is validated for use with a wide range of cell inputs.

The Centers for Disease Control and Prevention estimates more people get sick and die from drug-resistant germs than previously thought, the Washington Post reports.

According to the Associated Press, three universities and a healthcare institution are sharing a gift of $1 billion.

New rules seek to limit the type of scientific and medical research that can be used to guide public health regulations, the New York Times reports.

In Nature this week: FreeHi-C approach simulates Hi-C data from interacting genome fragments, and more.

Dec
02
Sponsored by
Sophia Genetics

This webinar will discuss how Moffitt Cancer Center has implemented a new capture-based application to accurately assess myeloid malignancies by detecting complex variants in challenging genes in a single experiment.  

Dec
04
Sponsored by
BC Platforms

This webinar will discuss what it takes to begin realizing precision medicine in a comprehensive clinical infrastructure, with insights from the Colorado Center for Personalized Medicine (CCPM).

Dec
10
Sponsored by
Congenica II

This webinar will discuss the use of next-generation sequencing and an optimized variant interpretation workflow to increase diagnostic yield in complex clinical cases.