Close Menu

Sartorius Incucyte SX5

May 07, 2020

Sartorius has launched its Incucyte SX5 Live-Cell Analysis system. The firm said that the tool applies novel optics, a new line of paired reagents, and purpose-built software to help researchers draw greater insights from live cell experiments. The Incucyte system has five different fluorescence channels, of which Sartorius said up to three can be used at once. Because the optical module uses long wavelength near infrared fluorescence, researchers will be able to image sensitive cell types on the platform up to months without requiring to be removed from the incubator. 

More Like This

Jul 01, 2020

Myriad Genetics Home Sample Collection Kit for GeneSight Psychotropic

Myriad Genetics has launched an at-home sample collection kit for its pharmacogenetic test GeneSight Psychotropic. The DNA sample for this test is typically collected in a physician's office, but the new kit will allow patients to use a cheek swab to collect their own sample from inside their cheeks and mail it to the Myriad Neuroscience CLIA and CAP accredited lab for analysis. Even though the new kit allows sample collection at home, the test still must be ordered by a licensed healthcare provider.

Mark Verratti, president of Myriad Neuroscience, said in a statement that during the COVID-19 pandemic there has been a rise in patients experiencing depression and anxiety, while at the same time more physicians are practicing telemedicine to limit patients' exposures to the virus. "To accommodate this growing need for remote access and innovative solutions, we created this easy-to-use patient collection kit," Verratti said. "This process allows clinicians to continue to use the GeneSight test as one tool at their disposal when developing a treatment plan for their patients suffering from depression or anxiety."

Jun 30, 2020

Twist Bioscience Respiratory Virus Research Panel

Twist Bioscience has launched the Twist Respiratory Virus Research Panel, a next-generation sequencing approach to detecting 29 common human respiratory viruses including SARS-CoV-2, several other coronaviruses, influenzas, rhinoviruses, and respiratory syncytial virus. The research-use-only panel will be bundled with an analysis platform from One Codex to enable a complete workflow beginning with Twist's target enrichment panel and ending with publication-ready visuals, the company said. The panel includes RNA- and DNA-based viruses in one kit with 41,047 nucleic acid probes, can detect as little as 100 copies of viral material, and has coverage of greater than 99.9 percent of the genome at 1X or greater post-enrichment.

Jun 30, 2020

Flagship Biosciences TissueInsight

Flagship Biosciences has launched a new clinical diagnostics immunooncology service called TissueInsight, which provides CLIA-reportable PD-L1 results along with data about a tumor's microenvironment to pathologists, oncologists, and immunologists, to aid them in optimizing care for cancer patients. TissueInsight gives rapid, data-rich tissue interpretation and removes the inherent variability of subjective manual tissue scoring. Along with its CLIA-reportable results, TissueInsight tumor microenvironment data includes information on tumor infiltrating lymphocytes and macrophages, the company said.

Jun 29, 2020

GenMark Diagnostics ePlex Respiratory Pathogen Panel 2

GenMark Diagnostics said its ePlex Respiratory Pathogen 2 (RP2) Panel is now available for US commercial distribution and clinical use. The panel is designed to provide results in less than two hours for SARS-CoV-2 and other common respiratory pathogens, including influenza, adenovirus, rhinovirus, and respiratory syncytial virus (RSV). 

GenMark said that earlier this month, it had applied to the US Food and Drug Administration for Emergency Use Authorization of its ePlex Respiratory Pathogen 2 Panel. In March, the company received EUA for its ePlex SARS-CoV-2 Test.

Jun 29, 2020

NeoGenomics InVisionFirst-Lung, NeoLab Solid Tumor Liquid Biopsy, Qiagen Therascreen PIK3CA RGQ PCR Kit

NeoGenomics announced the launch of three new liquid biopsy products for advanced non-small cell lung cancer, all solid tumor types, and breast cancer. The InVisionFirst-Lung liquid biopsy assay tests 37 genes related to the care of advanced NSCLC and covers all National Comprehensive Cancer Network guideline-recommended genomic drivers with targeted therapies for NSCLC. NeoGenomics partnered with Inivata to commercialize the test. 

The NeoLab Solid Tumor Liquid Biopsy is a next-generation sequencing test for genomic profiling of solid tumors. The test is part of the NeoLab suite of assays providing biomarker evaluation for patients with hematologic diseases who can't have a bone marrow biopsy and whose peripheral blood counts are low. 

The Qiagen Therascreen PIK3CA RGQ PCR kit is a companion diagnostic approved by the US Food and Drug Administration for use with alpelisib (Novartis' Piqray) that detects 11 clinically actionable mutations in the PIK3CA gene. NeoGenomics will launch the test in situations where PIK3CA testing can't be performed using tumor tissue due to insufficient samples, low quantities of tumor cells, or tissue sample decalcification. 

Jun 26, 2020

Oxford Nanopore Technologies Q Line

Oxford Nanopore Technologies has launched a number of nanopore sequencing products, called Q Line, for diagnostics and other regulated markets. The Q Line products are ISO9001-qualified and allow for sequencing in a locked-down, standardized format. They are designed for water testing, veterinary diagnostics, pharmaceutical research, industrial diagnostics, forensics, and clinical research applications. The first Q Line product is the GridIon Q, a locked-down version of the GridIon sequencer with an integrated compute system. It will be available with two kits, Ligation Sequencing Kit Q and Native Barcoding Expansion Q. More Q Line products will follow, including a MinIon MK1C Q, a Flongle Q, and additional kits.

Jun 25, 2020

Guardant Health GuardantInform

Guardant Health has launched a clinical-genomic database service it calls GuardantInform, intended to help accelerate research and development of the next generation of cancer therapeutics. The platform offers biopharma partners de-identified longitudinal clinical information and genomic data collected from the Guardant360 liquid biopsy test, which the firm has performed on more than 100,000 samples to date.

Among potential applications, Guardant highlighted targeted drug development, clinical trial optimization, and post-marketing pharma studies. According to the company, recent data presented at the AACR virtual annual meeting further support the database's potential in these areas.

Jun 23, 2020

LGC Maine Standards Validate ACTH Linearity and Calibration Verification Test Kits

LGC Maine Standards has released the Validate ACTH Linearity and Calibration Verification Test Kits to document linearity, for calibration verification, and for analytical measurement range verification of Adrenocorticotropic Hormone. The product provides five concentrations across the Elecsys-ATCH method on Roche's Cobas instrument and is formulated in a human plasma matrix. 

The product helps minimize manual dilutions and fulfills various quality control requirements, strengthening LGC's product range for endocrine testing, which includes 17 analytes. 

Jun 23, 2020

IDT gBlocks HiFi Gene Fragments

Integrated DNA Technologies has launched gBlocks HiFi Gene Fragments, double-stranded DNA fragments between 1,000 and 3,000 bp in length.

The fragments have an error rate of less than 1 in 12,000 bp and are verified with next-generation sequencing. Turnaround time is between six and 10 business days.

Applications include synthetic biology, pathway development, traditional cloning, and large construct assembly.

Jun 23, 2020

Seven Bridges Graf Genome Analysis

Bioinformatics firm Seven Bridges has made its graph-based genome analysis methods for population genomics available. The offering replaces the previous Graph Genome Suite.

Moreover, the company is offering its Graf Germline Variant Detection workflow and Pan Genome Reference to academic researchers for free.

Graf tools offer the ability to create population-specific genome graphs, curated genome graphs for rare disease, bespoke and family genome graphs for de novo mutation detection, and cancer and normal sample genome graphs for detecting somatic mutations in tumors.  

The tools improve genome analysis for people with non-European heritage, support more diverse population studies, and provide more accurate insertion and deletion calls.

Jun 23, 2020

Genedata Selector 6.0

Genedata has released its Selector 6.0 enterprise software for biopharmaceutical R&D. This newest version of Selector automates next-generation sequencing-based workflows with wizard-style playbooks that guide users through the entire workflow from sample registration to report generation, Genedata said. The workflows can be approved and locked for use in playbooks to minimize the risk of variations in data processing. Other new features include a configurable dashboard with status cards to provide scientists and managers quick access to project status and other information and a robust genome loading tool that enhances system performance and simplifies genome database maintenance, Genedata said.

Jun 19, 2020

HTG Molecular EdgeSeq Pan B-Cell Lymphoma Panel

HTG Molecular Diagnostics has pre-launched its HTG EdgeSeq Pan B-Cell Lymphoma Panel, which the firm expects to offer as a kit or as a service for research use only use starting in July. The panel is designed to provide molecular characterization of aggressive lymphomas by allowing researchers to measure the expression of genes linked to the aggressive lymphoma transcriptome. The panel is an extension of HTG's DLBCL assay. 

Jun 19, 2020

NanoString COVID-19 Disease Research Products

NanoString Technologies has launched a set of new solutions for studying immune response in COVID-19 disease research, which include the Host Response Gene Expression Panel and COVID -19 Panel Plus spike-in, as well as new protein and RNA content available on the GeoMx Digital Spatial Profiler.

The COVID-19 GeoMx-formatted Antibody Panel, from Abcam, provides a customizable panel which will be run with the GeoMx Immune Profiling Core to enable spatial analysis of 96 proteins involved in the immune response to SARS-CoV-2 infection. It is currently available through NanoString's GeoMx technology access program. The Host Response assay includes 770 genes focused on host susceptibility, interferon signaling, innate and adaptive immunity as well as other key areas of biology to characterize host response to infection. The COVID-19 panel contains probes targeting all SARS-CoV-2 genes as well as the host ACE receptor that is bound by the virus. 

Jun 19, 2020

LGC SeraCare AccuSet SARS-CoV-2 Performance Panel

LGC SeraCare has released the AccuSet SARS-CoV-2 Performance Panel, an eleven-member validation panel of undiluted, naturally occurring human plasma samples. Ten panel samples represent collections from multiple individuals positive for antibodies to SARS-CoV-2; a single negative sample is also included, according to the company's website. The panel is designed to support validation studies for SARS-CoV-2 diagnostic developers and to help meet assay verification requirements in clinical laboratories.

Jun 18, 2020

Novacyt Exsig Direct, Exsig Mag Extraction Kits; COVID-HT Test

Novacyt has launched two new extraction kits  Exsig Direct and Exsig Mag  for COVID-19 testing. The kits can be used with all open PCR instrument platforms. Exsig Direct is a direct-to-PCR extraction kit designed to be used with Novacyt's COVID-19 test. It employs a combination of optimized buffers to extract COVID-19 RNA from clinical samples. Exsig Mag runs on multiple automated magnetic bead extraction systems commonly used by clinical laboratories and has been developed to enhance extraction of COVID-19 RNA from clinical samples. Exsig Mag can be used with Novacyt's COVID-19 test or in combination with other COVID-19 PCR tests.

The firm has also launched a CE marked high-throughput SARS-CoV-2 PCR tests called COVID-HT.

Science reports that a new White House Office of Management and Budget memo rescinds previous ones that helped research institutions deal with pandemic-related closures.

Researchers report on a concerning strain of the H1N1 swine flu virus found among pigs in China, Agence France Presse reports.

The Associated Press reports that US officials are considering allowing pooled COVID-19 testing.

In Genome Research this week: Y chromosome gene expression analysis, de novo mutations rise with paternal age in rhesus macaques, and more.