Skip to main content
Premium Trial:

Request an Annual Quote

Sage Science SageHLS Platform

Sage Science has launched SageHLS, a platform designed to extract and purify extremely large DNA fragments directly from bacterial and tissue cultures, blood samples, or other cell sources. SageHLS can purify DNA into fragments ranging from 50 kilobases to 2 megabases, providing the long fragments needed for resolving haplotypes, structural variants, and other large or linkled genomic elements. For most samples, SageHLS can recover at least a microgram of DNA, a sufficient volume for common genome applications. Users can currently perform traditional library prep after purification on the platform, but later versions will directly incorporate this step for a more streamlined workflow, Sage Science said.

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.