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Sage Bionetworks Agora Platform

Sage Bionetworks has launched the Agora platform, a web-based tool that allows researchers to explore curated genomic analyses of Alzheimer's disease. The analyses resulted from the Accelerating Medicines Partnership – Alzheimer's Disease (AMP-AD) Target Discovery and Preclinical Validation Project, a public-private partnership led by the National Institute on Aging and managed by the Foundation for the NIH (FNIH). Through the Agora portal, which will be frequently updated, the analyses are now available to researchers outside the AMP-AD consortium. The initial release includes differential expression and co-expression network meta-analyses across four human RNA sequence data sets. Future releases will include human proteomic and metabolomic analyses, comparative evaluations of disease signatures across species, and druggability and tractability information to guide the selection of targets for early drug discovery.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.