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Roche Avenio Millisect System

Roche announced the commercial availability of the Avenio Millisect System, a tissue dissection instrument that utilizes an automated digitally assisted process to isolate clinically relevant cells from formalin-fixed paraffin-embedded tissue slides. The system is designed to address tissue dissection challenges in clinical labs where manual dissection lacks consistency and precision, and laser capture microscopy is cumbersome and costly, Roche said. Optimized to fit easily into a variety of clinical workflow configurations, the system allows precise and consistent recovery of regions of interest for molecular pathology, improving the results of diagnostic testing by reducing false negatives and allowing identification of additional potential therapeutic targets. The Avenio Millisect System is an IVD labeled medical device and is now available in the US and countries accepting the CE mark.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.