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The Repositive Platform

Repositive has launched the full version of its free online data platform, which has been in beta since last year. The platform offers access to more than 750,000 datasets on DNA and RNA-sequencing, epigenetics, and the microbiome. It also features tools such as Boolean and predicated search capacity, improved curation of search filters, the ability to browse through datasets without a keyword search, and options for third party sign-up and login through Google+ and LinkedIn. The company further intends to launch specialized collections of data starting with the Chinese Control Data — a dataset that contains information from GenomeAsia, SGVP, GigaDB, and the Kadoorie BioBank — which will be available this month. Repositive plans to release specialized collections of DNA methylation, RNA expression, PDX molecular data, and human gut microbiome datasets later this year.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.