Skip to main content
Premium Trial:

Request an Annual Quote

Reaction Biology/4HF Biotec Cell-Based Bioinformatics Service

Drug-discovery CRO Reaction Biology and informatics company 4HF Biotec have introduced a cell-based bioinformatics service that combines Reaction's ProLiFiler cell assay service with 4HF Biotec's Biomarker Analysis and MA Finder informatics tools to help inform drug discovery. Biomarker Analysis searches for mutations, gene copy numbers, and gene expression data, while MoA Finder scans test results to pinpoint modes of action in experimental drug compounds. The service, aimed at the oncology market, will be run at Reaction Biology's lab in Freiburg, Germany.

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.