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Reaction Biology/4HF Biotec Cell-Based Bioinformatics Service

Drug-discovery CRO Reaction Biology and informatics company 4HF Biotec have introduced a cell-based bioinformatics service that combines Reaction's ProLiFiler cell assay service with 4HF Biotec's Biomarker Analysis and MA Finder informatics tools to help inform drug discovery. Biomarker Analysis searches for mutations, gene copy numbers, and gene expression data, while MoA Finder scans test results to pinpoint modes of action in experimental drug compounds. The service, aimed at the oncology market, will be run at Reaction Biology's lab in Freiburg, Germany.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.