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Promega's PowerPlex Fusion 6C System

Promega has released the PowerPlex Fusion 6C System for forensic casework samples. The PowerPlex Fusion 6C is a six-color, 27-locus multiplex system. It combines common and informative loci to overcome typical challenges faced by laboratories, including sample inhibitors, low levels of input DNA, degradation, and mixtures, Promega said. Two rapidly-mutating Y-STR loci, DYS570 and DYS576, are included in the multiplex for improved mixture interpretation, the firm said, and the system offers rapid-cycling protocols of approximately one hour.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.