Promega LMR MSI Analysis System
Promega has launched its LMR MSI Analysis system, a PCR-based research tool with novel markers for detecting microsatellite instability. The panel consists of eight total markers: four gold-standard markers (BAT-25, BAT-26, MONO-27, and NR-21) and four novel long mononucleotide repeat markers (BAT-52, BAT-56, BAT-59, and BAT-60). According to the company combining these marker sets expands MSI detection ability in difficult samples while maintaining overlap with data gathered using traditional markers. Promega said that the assay has been optimized to enable strong and balanced amplification even from degraded samples such as formalin-fixed, paraffin-embedded tissue.