Predictive Biotech's Spine Deformity MDx Test

May 19, 2016

Predictive Biotech, a subsidiary of Predictive Technology Group, has beta launched its new Spine Deformity Test developed to predict the severity of spine deformities and syndromes. The test uses genotype analysis to identify single nucleotide polymorphisms (SNPs) and SNP halotypes in order to diagnose individuals with spine deformities, such as scoliosis.

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Apr 20, 2017

Invitae Immunologic, Metabolic, Newborn Screening Confirmation Panels

Invitae announced it has added 80 new panels and updated 24 panels for the diagnosis of inherited immunologic and metabolic disorders, as well as panels that confirm diagnoses suggested by newborn screening. Some of these offerings include new and updated lysosomal storage disorder panels covering 52 genes; an updated, 90-gene newborn screening confirmation panel; a new panel of 133 genes for diagnosing treatable neurometabolic disorders; a new panel of more than 200 genes linked to primary immunodeficiencies; and a new 46-gene panel for associated monogenic forms of inflammatory bowel disease. Additionally, the firm includes deletion/duplication analysis at no extra charge in an effort to identify between 5 percent and 10 percent of pathogenic variants that are difficult to gauge with next-generation sequencing. 

Apr 20, 2017

Biogazelle mRNA Sequencing

Biogazelle has launched its mRNA sequencing service for human plasma and other bodily fluids. The company uses massively parallel sequencing to quantify and characterize mRNA molecules in low volumes of plasma and can detect between 6,000 and 8,000 genes, it said. This type of analysis provides an order of magnitude more biomarkers than microRNA sequencing, and since it is a liquid biopsy-based technology it allows for serial follow-up of patients to monitor them for disease, the company added.

Apr 12, 2017

Diatech Pharmacogenetics EasyPGX kits, Helix cfDNA kit

Italy's Diatech Pharmacogenetics has launched a line of PCR-based oncology kits. The easyPGX line of PCR kits includes assays to detect KRAS, NRAS, BRAF, EGFR, involved in many solid tumors; DPYD and UGT1A1 variants associated with toxicity upon fluoropyrimidine and irinotecan treatment, respectively; and a thyroid panel. The sensitivity of the assays is as low as 0.5 percent, and the starting material can be DNA extracted from fresh, frozen, and formalin-fixed paraffin-embedded tissues, and plasma; and genomic DNA from whole blood for the DPYD and UGT1A1 kits. Reagents are delivered in eight-well strips pre-loaded with a complete master mix in a dry format that is stable at room temperature. The tests have a turnaround time of less than 3 hours, including deparaffinization and lysis, and require less than 10 minutes of hands-on time. In addition, the company has launched the Helix kit for the extraction of circulating free DNA. This kit can be used with 1 to 5 ml of fresh or frozen plasma and has a turnaround time of less than 3 hours.

Apr 12, 2017

Helomics D-Chip

Helomics launched D-Chip, a searchable bioinformatics platform for mining proprietary multi-omic and clinical data on cancer patients. The technology can be used by diagnostic and drug firms doing biomarker discovery and development, virtual clinical trials, and patient recruitment and selection. 

Apr 12, 2017

Prenetics ONEdna DNA Screening Test Service

Prenetics has launched ONEdna, a DNA screening test service. The screening service provides consumers with a comprehensive view and analysis of an individual's genes along with actionable recommendations, the company said. The results may include insight into health status and risk for disease, optimal diet and nutrition, indications about how a patient may respond to various medications, and identification of the patient's risk of common cancers.

Apr 10, 2017

NuGen Technologies RNA-seq Kits

NuGen Technologies has launched two RNA sequencing kits: Universal Plus mRNA-seq and Trio RNA-seq. The Universal Plus mRNA-seq kit includes the option of eliminating unwanted transcripts after library construction using the company's proprietary AnyDeplete technology. This improves the ability to detect low expressed genes. The kit also enables input in the range of 1 microgram down to 10 nanograms. Trio RNA-seq is a whole-transcriptome kit that is suited for applications with low-abundance transcripts. It incorporates three technologies: single-primer isothermal amplification, DimerFree technology in the library prep step to minimize adapter dimers, and AnyDeplete.

Apr 05, 2017

LifeLabs Genetic Counseling

LifeLabs launched its genetic counseling service for patients in Canada undergoing BRCA1/2 testing, as part of the firm's BRCA testing service. The service is available on a pre- and posttesting basis. The BRCA1/2 testing is provided by LifeLabs' partner, Centogene. 

Apr 05, 2017

Paragon Genomics CleanPlex Target Enrichment Solution

Paragon Genomics has launched its CleanPlex target enrichment solution. The product uses the company's patented amplicon sequencing technology which effectively removes nonspecific PCR products generated during highly multiplexed PCR reactions. This 10-minute digestion step is crucial in achieving high-quality libraries before targeted sequencing, the company said. It removes DNA fragmentation, hybridization, and ligation processes associated with traditional hybrid capture-based methods.

Apr 05, 2017

Bionano Genomics Genomic Analysis Tools Suite

Bionano Genomics has launched a new suite of genomic analysis software, Bionano Access 1.0 and Bionano Solve 3.0. Bionano Access replaces IrysView software for Irys users and centralizes all software needed to generate, edit, analyze, and visualize genome maps. It also comes with a powerful variant annotation pipeline that can filter out common variants based on a database of controls, analyze trios or two samples to identify inherited and de novo structural variants, and visualize and export in a dbVar-compliant VCF file for downstream analysis. Bionano Solve 3.0 is an assembly pipeline within Bionano Access that allows users to run SV analysis or hybrid scaffolding. It also significantly improves the hybrid scaffolding application by integrating two genome maps created separately with different nicking enzymes.

Apr 05, 2017

UgenTec Interpretation Solution for PathoFinder PCR 2SMART Assays

UgenTec and PathoFinder have launched a cloud-based CE-IVD interpretation solution for PathoFinder's next generation multiplex PCR 2SMART assays. The solution uses UgenTect software to automate the interpretation of pathogens detected in PathoFinder's syndromic infectious disease panels. The solution has been rolled out to more than ten laboratories across Europe and the Middle East.

Apr 04, 2017

Strand Life Sciences StrandNGS v3.0

Strand Life Sciences has released version 3.0 of StrandNGS its flagship, next-generation sequencing data analysis and visualization platform. The firm has enhanced accuracy, precision, and speed. The new version also includes a "one shot pipeline execution option," improved RNA-Seq workflow processing speed, and full support for HGVS notation to support variant reporting and information exchange in DNA diagnostics.

Mar 31, 2017

Genetic Signatures EasyScreen STI/Genital Pathogen Detection Kit

Genetic Signatures has launched the EasyScreen STI Kit to simultaneously detect the 12 most commonly encountered sexually transmitted infections. The kit runs on standard lab equipment and the firm's proprietary 3base method, which reduces genetic information complexity and delivers accurate results in hours. The kit will initially be available for research use only until regulatory approvals are gained in Australia and the EU, and the 12 targets detected by the kit will also be available as analyte specific reagents in the US.

Mar 31, 2017

Swift Biosciences Accel Amplicon CFTR Panel and Accel-NGS XL Library Prep Kit

Swift Biosciences has launched the Accel Amplicon CFTR panel, which detects a wide range of variants and mutants in all exonic and select intronic regions of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. It produces sequence libraries in two hours, allows the user to process three to four times more libraries per day, and requires as little as 10 nanograms of sample input from either whole blood, dried blood spots, saliva, or buccal swabs.

The company has also launched the Accel-NGS XL Library Prep kit, which optimizes library preparation, particularly for the PacBio's Single Molecule, Real-Time SMRT sequencing. The kit provides longer sequencing reads with a single-tube workflow.

Mar 30, 2017

FlowJo SeqGeq

FlowJo has launched SeqGeq, a platform-agnostic desktop application for analysis of single-cell omics data. It offers tools to identify subpopulations of cells based on a variety of genes and synthetic parameters, to compare clusters and identify differentially-expressed genes or pathways of interest, and to generate publication-ready heatmaps and figures using a drag-and-drop layout editor. The application accepts a variety of data types, including scRNA-seq, RNA-Seq, and microarray data.

Mar 30, 2017

NanoString nCounter Enhancement Kits and Gene Expression Panels

NanoString has launched a new nCounter mRNA amplification kit, a universal cell capture kit, and two new nCounter assays. The nCounter Low RNA Input Kit employs multiplexed target enrichment to linearly amplify mRNA transcripts, enabling gene expression analysis with 1 nanogram to 10 nanograms of sample inputs. The kit is compatible with both pre-defined and custom panels. The Intracellular Compatible Universal Cell Capture Kit enables researchers to use the nCounter Vantage RNA:Protein Immune Cell Signaling Assay with as few as 20,000 cells. NanoString is also releasing two new assays. The RNA MAPK-PI3K Pathways panel provides a curated gene set to measure transcriptional activity of those pathways. The firm is also offering a gene expression panel for myeloid cell innate immune response in humans or mice, developed in partnership with Lisa Coussens of Oregon Health and Sciences University.

Mary Beckerle has been removed as director of the Huntsman Cancer Institute in what one researcher refers to as a "coup," ScienceInsider reports.

Bill Gates tells the Telegraph that bioterrorism is a serious risk.

The March for Science is to take place tomorrow, and supporters are tapping their creative energies to create placards to carry.

CBS News reports that the White House Science Fair is to continue under President Donald Trump.

Apr
27
Sponsored by
SeraCare

This webinar is the third in a four-part series highlighting real-world examples of how some lab directors are bringing validated next-generation sequencing-based tests to the clinic.

May
09
Sponsored by
SeraCare

This webinar is the last in a four-part series highlighting real-world examples of how some lab directors are bringing validated next-generation sequencing-based tests to the clinic.