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Phase Genomics ProxiMeta Hi-C

Phase Genomics has launched ProxiMeta Hi-C, a service that employs Hi-C sequencing on metagenomic samples to obtain complete individual genomes without culturing or high molecular weight DNA extraction. ProxiMeta Hi-C is based on capturing DNA with in vivo Hi-C so sequence reads can be traced back to their cell of origin. Researchers from the University of Washington first described the approach in 2014 in G3: Genes Genomes Genetics.

The Scan

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.

DNA Biobank Developed for French Kidney Donors, Recipients

The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France.

Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut

By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site.

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.