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PerkinElmer Assay Kits for GPCR Therapeutic Discovery

PerkinElmer has launched new assay kits to further G protein-coupled receptor (GPCR) therapeutics discovery. The kits include the HTRF GTP Gi binding kit (a time-resolved Förster resonance energy transfer-based assay for GTP binding); the B-arr2 recruitment kit; and HTRF total kits for beta-arresting 1, beta-arrestin 2, and AP2. The assays are intended to help scientists better understand the role GPCRs play in disease by studying the interaction, expression, and potential modulation of intracellular proteins involved in GPCR signaling mechanisms.

The Scan

Boosters Chasing Variants

The New York Times reports that an FDA advisory panel is to weigh updated booster vaccines for COVID-19.

Not Yet

The World Health Organization says monkeypox is not yet a global emergency, the Washington Post reports.

More Proposed for Federal Research

Science reports that US House of Representatives panels are seeking to increase federal research funding.

PLOS Papers on Breast Cancer Metastasis, Left-Sided Cardiac Defects, SARS-CoV-2 Monitoring

In PLOS this week: link between breast cancer metastasis and CLIC4, sequencing analysis of left-sided cardiac defects, and more.