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Paragon Genomics CleanPlex UMI Lung Cancer Panel

Paragon Genomics will introduce its research-use-only CleanPlex UMI Lung Cancer Panel at the upcoming American Society of Human Genetics Meeting. The panel is a targeted resequencing assay designed for the detection of ultralow-frequency variants across the hotspot regions of 23 genes frequently associated with lung cancer. The CleanPlex UMI technology incorporates unique molecular identifiers that distinguish between the two strands of DNA, enabling correction of PCR and sequencing errors to achieve more accurate results. The product can be used to prepare sequencing-ready libraries in a single-tube format in 3.5 hours, and variants at 0.1 percent allele frequency can be detected with high specificity using only 30 ng of DNA, Paragon said. CleanPlex NGS Panels are available for use with Illumina or Life Technologies Ion Torrent platforms.

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.