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Paragon Genomics CleanPlex Target Enrichment Solution

Paragon Genomics has launched its CleanPlex target enrichment solution. The product uses the company's patented amplicon sequencing technology which effectively removes nonspecific PCR products generated during highly multiplexed PCR reactions. This 10-minute digestion step is crucial in achieving high-quality libraries before targeted sequencing, the company said. It removes DNA fragmentation, hybridization, and ligation processes associated with traditional hybrid capture-based methods.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.