Skip to main content
Premium Trial:

Request an Annual Quote

Paragon Genomics CleanPlex CFTR Panel

Paragon Genomics this week introduced the CleanPlex CFTR Panel for cystic fibrosis testing. The panel uses the company's CleanPlex target enrichment technology for a multiplex PCR-based targeted sequencing assay to evaluate somatic and germline variants in the CFTR gene. It covers all exons of the gene and includes mutations recommended by the American College of Medical Genetics and Genomics.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.