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Paradigm Diagnostics PCDx Tests

Paradigm Diagnostics said that all of its Paradigm Cancer Diagnostic (PCDx) tests ordered for lung cancer patients now also include 17 fusions, as well as EGFR and MET skipping events. The fusions include: ALK, AXL, BRAF, CCND1, FGFR1, FGFR2, FGFR3, MET, NGR1, NTRK1, NTRK2, NTRK3, PPARG, RAF1, RET, ROS1 and THADA. The fusion panel may also be ordered as an add-on for any PCDx patients and will be delivered within in the company's standard five-day turnaround time. The assay uses anchored PCR technology on RNA to detect known and novel fusions with high sensitivity with a tissue requirement of 4 percent or greater tumor content in a single core needle biopsy or fine needle aspirate.

The Scan

US Supports Patent Waivers

NPR reports that the Biden Administration has announced its support for waiving intellectual property protections for SARS-CoV-2 vaccines.

Vaccines Versus Variants

Two studies find the Pfizer-BioNTech SARS-CoV-2 vaccine to be effective against viral variants, and Moderna reports on booster shots to combat variants.

CRISPR for What Ails You

The Wall Street Journal writes that CRISPR-based therapies could someday be used to treat common conditions like heart attacks.

Nature Papers Review Integration of Single-Cell Assay Data, Present Approach to Detect Rare Variants

In Nature this week: review of ways to integrate data from single-cell assays, and more.