Skip to main content
Premium Trial:

Request an Annual Quote

Pacific Biosciences Sequel IIe System, SMRT Link 10 Software

Pacific Biosciences has launched the Sequel IIe system. This updated version of the Sequel II single-molecule sequencing instrument is optimized to generate the firm's HiFi reads directly. The Sequel IIe eliminates the need for post-processing and can reduce secondary analysis time by up to 70 percent, with up to a 90 percent reduction in file transfer and data storage costs.

PacBio has also added new tools to its SMRT Link software to enable complete workflow integration on Amazon Web Services cloud computing and a new genome assembly analysis application for generating reference-quality de novo assemblies from HiFi reads.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.