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Pacific Biosciences Sequel IIe System, SMRT Link 10 Software

Pacific Biosciences has launched the Sequel IIe system. This updated version of the Sequel II single-molecule sequencing instrument is optimized to generate the firm's HiFi reads directly. The Sequel IIe eliminates the need for post-processing and can reduce secondary analysis time by up to 70 percent, with up to a 90 percent reduction in file transfer and data storage costs.

PacBio has also added new tools to its SMRT Link software to enable complete workflow integration on Amazon Web Services cloud computing and a new genome assembly analysis application for generating reference-quality de novo assemblies from HiFi reads.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.