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Pacific Biosciences Sequel II System

Pacific Biosciences has launched it Sequel II single-molecule sequencing instrument. The new system runs SMRT chips that contain 8 million wells, or zero-mode waveguides (ZMWs). The system delivers around eight times greater data output than the firm's original Sequel instrument, which had 1 million ZMWs. According to the company, its HiFi reads, which make use of PacBio's circular consensus sequencing (CCS) protocol, have greater than 99.9 percent accuracy. As of last month, five early access customers had run 58 SMRT cells, obtaining average yields per SMRT cell for the CCS protocol of 250.4 gigabases and average per-cell yields for its continuous long read protocol of 67.4 gigabases.

The Scan

Vaccine Update Recommended

A US Food and Drug Administration panel recommends booster vaccines be updated to target Omicron, CNBC reports.

US to Make More Vaccines for Monkeypox Available

The US is to make nearly 300,000 vaccine doses available in the coming weeks to stem the spread of human monkeypox virus, according to NPR.

Sentence Appealed

The Associated Press reports that Swedish prosecutors are appealing the sentence given to a surgeon once lauded for transplanting synthetic tracheas but then convicted of causing bodily harm.

Genome Biology Papers on COVID-19 Effector Genes, Virtual ChIP-seq, scDART

In Genome Biology this week: proposed COVID-19 effector genes, method to predict transcription factor binding patterns, and more.