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Pacific Biosciences Microbial Multiplexing Kit

Pacific Biosciences has a launched a microbial multiplexing kit for its single-molecule sequencing instrument Sequel. The kit includes two new validated barcoded adapter kits and makes use of PacBio's new Sequel Binding/Sequencing Kit 2.1 and its analysis software SMRT Link version 5.1.0, according to the company. Multiplexing is done by incorporating a unique barcode for each microbe into the SMRTbell adapters after shearing genomic DNA. The process does not require PCR amplification, so epigenetic information is preserved.

The Scan

Booster Push

New data shows a decline in SARS-CoV-2 vaccine efficacy over time, which the New York Times says Pfizer is using to argue its case for a booster, even as the lower efficacy remains high.

With Help from Mr. Fluffington, PurrhD

Cats could make good study animals for genetic research, the University of Missouri's Leslie Lyons tells the Atlantic.

Man Charged With Threatening to Harm Fauci, Collins

The Hill reports that Thomas Patrick Connally, Jr., was charged with making threats against federal officials.

Nature Papers Present Approach to Find Natural Products, Method to ID Cancer Driver Mutations, More

In Nature this week: combination of cryogenic electron microscopy with genome mining helps uncover natural products, driver mutations in cancer, and more.