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OriCiro Genomics Cell-Free Cloning System

OriCiro Genomics has launched its Cell-Free Cloning System, the world's first technology enabling cell-free amplification of large circular DNA, eliminating the reliance on Escherichia coli cloning. Thes ystem comprises the OriCiro Assembly Kit and OriCiro Amp Kit. A simple two-step in vitro process enables cell-free assembly and amplification of circular DNA molecules without the need for E. coli transformation and culture, the company said.

The Scan

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.

Study Examines Relationship Between Cellular Metabolism, DNA Damage Repair

A new study in Molecular Systems Biology finds that an antioxidant enzyme shifts from mitochondria to the nucleus as part of the DNA damage response.

Stem Cell Systems Target Metastatic Melanoma in Mouse Model

Researchers in Science Translational Medicine describe a pair of stem cell systems aimed at boosting immune responses against metastatic melanoma in the brain.

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.