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OncoDNA OncoDeep

OncoDNA has released an updated version of its OncoDeep solid tumor analysis tool. The firm's OncoDeep assay sequences a total of 313 genes, compared to 75 for the original product. The panel includes more genes involved in immunotherapy selection and homologous recombination deficiency for PARP inhibitors. OncoDNA said that the next-generation sequencing panel has a broader detection of fusions with new probes, as well as a broader MSI coverage to increase the accuracy of the firm's algorithm.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.