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OmniTier CompStor Assembly

OmniTier has introduced CompStor Assembly for de novo DNA assembly and reference alignment. Designed for short-read next-generation sequencing data, CompStor Assembly reduces assembly times and improves assembly quality on low-cost hardware compared to currently available assemblers, the company said. Using CompStor Assembly and eight CompStor Assembly server nodes, de novo assembly of a human genome can be achieved in about eight minutes. This performance equals the assembly time previously achieved with the NERSC's Cray XC30 advanced supercomputer, using 15,360 processor cores and DRAM-based algorithm implementations, OmniTier noted. By contrast, CompStor Assembly nodes are standard servers based on low-cost x86 Intel processors and tiered DRAM and NVMe SSDs.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.