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OmniSeq Immune Report Card

OmniSeq has launched its Immune Report Card, an immune profiling test designed to help oncologists select the best mono and combination immunotherapy options for patients. The assay integrates five clinical-grade tests that together provide a comprehensive immune profile. The report card includes CD3/8 and PD-L1 immunohistochemistry, PD-L1/2 copy number using in situ hybridization, microsatellite instability testing, mutational burden analysis via Thermo Fisher Scientific's Ion Torrent next-generation sequencing of 409 exon cancer genes, and cross-validated simultaneous gene expression analysis of 54 critical transcripts via targeted RNA-seq using the Oncomine Immune Response Research Assay. The test is approved by the New York State Clinical Laboratory Evaluation Program, the company said.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.