OmniSeq Immune Report Card

Jun 14, 2017

OmniSeq has launched its Immune Report Card, an immune profiling test designed to help oncologists select the best mono and combination immunotherapy options for patients. The assay integrates five clinical-grade tests that together provide a comprehensive immune profile. The report card includes CD3/8 and PD-L1 immunohistochemistry, PD-L1/2 copy number using in situ hybridization, microsatellite instability testing, mutational burden analysis via Thermo Fisher Scientific's Ion Torrent next-generation sequencing of 409 exon cancer genes, and cross-validated simultaneous gene expression analysis of 54 critical transcripts via targeted RNA-seq using the Oncomine Immune Response Research Assay. The test is approved by the New York State Clinical Laboratory Evaluation Program, the company said.

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Jun 19, 2018

GenomeDx Biosciences, Pathnostics Guidance test

GenomeDx Biosciences and Pathnostics have launched the Guidance test for patients with simple cystitis, recurrent, persistent or complicated urinary tract infections, prostatitis, and interstitial cystitis. The test is performed by Pathnostics and distributed by GenomeDx urologists. Guidance is a rapid diagnostics test for personalizing treatment options by identifying 42 pathogens. It also determines antibiotic sensitivity of the pathogens and assesses the presence of antibiotic-resistant genes. Result are available 24 to 48 hours after a patient's specimen arrives at the lab. 

Jun 18, 2018

Twist Bioscience High-Throughput Human Core Exome Kit

Twist Bioscience announced a high-throughput version of its Twist Human Core Exome Kit for next-gen sequencing library preparation and target enrichment. The new kit allows customers to run up to 96 samples simultaneously.  

Jun 18, 2018

Thermo Fisher Scientific Ion AmpliSeq HD

Thermo Fisher Scientific has launched Ion AmpliSeq HD, a new library preparation technology for customized next-generation sequencing gene panels. It allows customers to design panels to detect single nucleotide variants, small indels, fusions, and copy number variants with a limit of detection as low as 0.1 percent in blood samples and has applications in both oncology research and inherited disease research.

Jun 15, 2018

New England Biolabs NEBNext Single Cell/Low Input RNA

New England Biolabs has launched the NEBNext Single Cell/Low Input RNA library prep kit for Illumina sequencing instruments. The kit makes use of an optimized template switching protocol as well as NEB's Ultra II FS enzymatic DNA fragmentation technology. It is amenable to single cells and ultra-low input RNA. The workflow requires between 2 picograms and 200 nanograms of input RNA.

Jun 15, 2018

CoreBiome BoosterShot and StrainView Metagenomics Services

CoreBiome has launched services for shotgun metagenomics and strain sequencing for $99. The services enable species and gene profiling for the human microbiome and deep characterization of microbial isolate libraries, according to the company.

The shotgun sequencing service, BoosterShot, has a turnaround time of three weeks from sample receipt to online report and sequences to a depth of 2 million reads per sample. In addition, it has launched StrainView for whole-genome shotgun sequencing of up to thousands of isolated bacterial genomes.

Jun 14, 2018

Agilent In Situ Hybridization Probes

Agilent Technologies released a range of new probes for in situ hybridization. The probes address the need to cleanly and accurately interpret data from fluorescence in situ hybridization and chromogenic in situ hybridization, Agilent said. The new Agilent SureFISH probes include Break-Apart: MALT1, BCL2, BCL6, CCND1, MYC, IGH, Dual Fusion: IGH/CCND1, IGH/MYC, and IGH/BCL2. The new CISH probes include (ASR) EBER RNA CISH and Kappa and Lambda mRNA CISH probes.

Jun 12, 2018

Biocept CEE-Sure Blood Collection Tubes

Biocept has launched its CEE-Sure blood collection tubes for research use only. Under a previously-announced distribution agreement, the tubes are being internationally distributed through VWR, a leading global provider of product and service solutions to laboratory and production customers. Specimen types that can be transported include blood, cerebrospinal fluid, sputum, and fluid obtained from pleural effusion. The tubes employ a patented media that inhibits cell clumping, preventing clogging of microfluidics devices used in circulating tumor cell analyses. They can also preserve high-quality circulating cfDNA for advanced molecular testing applications like non-invasive prenatal testing and detection of gene mutations in cancer. 

Jun 11, 2018

Molecular Health Guide Version 3.0

Molecular Health has released version 3.0 of its Molecular Health Guide software platform for precision medicine. According to the company, the new release offers improved biomarker classification and now supports Human Genome Variation Society nomenclature, allowing users to incorporate other diagnostic test results into MH Guide reports, which combine patient-specific molecular data with biomedical knowledge to assist physicians in choosing treatments. MH Guide is registered as an in vitro diagnostic device in the European Union.

Jun 08, 2018

Qiagen QIAseq 16S/ITS NGS Panels, UCP Multiplex PCR kit

Qiagen has launched panels and kits for microbial community profiling from complex microbiome samples that are designed to reduce profiling bias. The QIAseq 16S/ITS NGS Panels can profile bacterial and fungal communities by interrogating combinations of nine bacterial 16S variable regions as well as fungal ITS regions using Illumina platforms. Users can index from 24 to 384 samples in a panel. The UCP Multiplex PCR Kit is a stand-alone product as well as a component of the QIAseq 16S/ITS Panels. The PCR master mix can be used on difficult microbial samples and features nucleic acid-depleted reagents that are tested for bacterial and fungal DNA contamination and inhibitor-resistant amplification for templates with up to 70 percent GC content.

Jun 07, 2018

Curetis Unyvero System, Lower Respiratory Tract Infection Cartridge

Curetis has announced the US commercial launch of its molecular diagnostic Unyvero System and the Unyvero LRT Application Cartridge, a test cartridge to detect lower respiratory tract infections. The cartridge, which was cleared together with the system by the US Food and Drug Administration earlier this year, covers more than 90 percent of infection cases of hospitalized pneumonia patients, detecting pathogens and genetic resistance markers directly from aspirate samples in less than five hours.  

Jun 07, 2018

Pacific Biosciences Microbial Multiplexing Kit

Pacific Biosciences has a launched a microbial multiplexing kit for its single-molecule sequencing instrument Sequel. The kit includes two new validated barcoded adapter kits and makes use of PacBio's new Sequel Binding/Sequencing Kit 2.1 and its analysis software SMRT Link version 5.1.0, according to the company. Multiplexing is done by incorporating a unique barcode for each microbe into the SMRTbell adapters after shearing genomic DNA. The process does not require PCR amplification, so epigenetic information is preserved.

Jun 06, 2018

Databricks Unified Analytics Platform for Genomics

Databricks has launched the Databricks Unified Analytics Platform for Genomics. The cloud-based platform provides collaborative workspaces prebuilt with genomic pipelines and tertiary analytics optimized to run at massive scale. Healthcare and life science organizations can easily build, scale, and deploy critical genomic analytics and machine learning models in minutes, Databricks noted. The platform also enables these organizations to process and analyze large-scale genomics data up to 100X faster than existing solutions, the company claimed.

Jun 06, 2018

Synthego Engineered Cells Portfolio

Synthego has launched its Engineered Cells product portfolio, giving customers immediate access to Knockout Clone and Pool, and Advanced Cells. The Knockout Cell Pools provide researchers the ability to purchase engineered cell populations with a first-ever guaranteed knockout frenquency of 50 percent or greater with a single click. These engineered cells will be delivered in as few as four weeks. The high knockout frequency allows researchers to use the pools directly in many assays or efficiently generate clonal populations.

Knockout Cell Clones give researchers the most complete access to CRISPR with no additional steps required. These engineered cell clones are 100 percent sequence verified to contain the gene of interest knocked out and are delivered in as few as eight weeks.

Advanced Cells are optimal for researchers working on more complex gene editing projects, the company said. Researchers can use Synthego's expertise to design, execute, and analyze genome editing projects that go beyond single-gene knockouts, including knock-ins (protein modifications, protein tagging, transgene insertions) and editing complex primary cells and stem cells.

Jun 05, 2018

Fluidigm Advanta Sample ID Genotyping Panel

Fluidigm has launched the Advanta Sample ID Genotyping Panel for the identification and quality assessment of human samples and cell lines in disease research. Developed for use with the Biomark HD system, the Advanta panel enables laboratories to accurately detect a unique genetic fingerprint from samples at each stage of their journey. The panel design contains 96 different SNP variants, including 80 synonymous human variants located in exonic regions of the genome; 10 quality assessment variants; and six gender-confirming variants. New targets for specific sample populations also can be added to customize the panel based on specific study goals, Fluidigm noted.


Jun 04, 2018

OmniSeq Advance

Roswell Park Comprehensive Cancer Center subsidiary OmniSeq and the Laboratory Corporation of America have launched a molecular cancer assay, OmniSeq Advance. The test involves next-generation sequencing and immunohistochemistry to assess specific genomic alterations, tumor mutational burden, microsatellite instability, the tumor microenvironment, and markers associated with immunotherapy. LabCorp will distribute the test.

Oxford Nanopore Technologies is looking into dual listings in London and Hong Kong, according to the South China Morning Post.

The New York Times looks into medical research funding in the US and how the grant system might not be funding the best work.

US lawmakers proposed increasing the National Science Foundation budget, including its facilities account, Science reports.

In PNAS this week: effects of gene deletions on bacterial metabolic networks, genetic responses to sea star wasting disease, and more.

Jun
20
Sponsored by
PerkinElmer

In this webinar, Michael Quail of the R&D Sequencing team at the Wellcome Trust Sanger Institute will provide an expert perspective on library prep for next-generation sequencing.

Jun
21
Sponsored by
Roche

This webinar will provide a detailed look at how a genomics lab implemented next-generation sequencing (NGS) liquid biopsy assays into its in-house clinical research program.

Jun
26
Sponsored by
Lexogen

This webinar outlines a study that sought to characterize the landscape of alternative polyadenylation (APA) in the lung cancer transcriptome in order to gain insight into the role of APA in cancer progression.

Jun
28
Sponsored by
PerkinElmer

This webinar will review a standardized, high-throughput, and fully automated library prep protocol for human metagenomic analysis.