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Olink Proteomics Explore 1536 Assay

Sweden's Olink Proteomics has launched the Olink Explore 1536, a multiplex, proximity-extension immunoassay with next-generation sequencing readout on the Illumina NovaSeq platform. The semi-automated assay can measure more than 1,460 human proteins from less than 3 microliters of plasma or serum, enabling more than 1.35 million protein measurements per week per NGS system. These curated proteins provide coverage of the low-abundance plasma proteome. Olink is offering the assay as a service performed at the firm's labs in Sweden and Boston.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.